ECG T-Wave Monitor for Potential Early Detection and Diagnosis of Cardiac Arrhythmias.
Summary of "ECG T-Wave Monitor for Potential Early Detection and Diagnosis of Cardiac Arrhythmias."
T-wave abnormalities are gaining significance in the realm of electrocardiogram diagnostics. In particular, T-wave alternans are proving to be powerful predictive indicators of potentially fatal arrhythmias. T-wave morphology monitoring and analysis are the means by which alternans and other abnormalities are detected. We have presented a preliminary design of an analog T-wave monitor to provide a characteristic description of the beat-to-beat T-wave morphology in terms of its maximum leading edge and trailing edge slopes, and its area. Experimental results showed that data from the analog T-wave monitor compared well with those predicted theoretically. Current design of the T-wave monitor, once improved, can find use in the screening, diagnosis, and early detection of T-wave abnormalities in clinical settings.
Affiliation
Cardiovascular Engineering Laboratory, Department of Biomedical Engineering, Rutgers University, 599 Taylor Road, Piscataway, NJ, 08854, USA, dwsmit07@eden.rutgers.edu.
Journal Details
This article was published in the following journal.
Name: Cardiovascular engineering (Dordrecht, Netherlands)
ISSN: 1573-6806
Pages:
Links
- PubMed Source: http://www.ncbi.nlm.nih.gov/pubmed/21140289
- DOI: http://dx.doi.org/10.1007/s10558-010-9106-z
Medical and Biotech [MESH] Definitions
Early Diagnosis
Methods to determine in patients the nature of a disease or disorder at its early stage of progression. Generally, early diagnosis improves PROGNOSIS and TREATMENT OUTCOME.
Arrhythmias, Cardiac
Any disturbances of the normal rhythmic beating of the heart or MYOCARDIAL CONTRACTION. Cardiac arrhythmias can be classified by the abnormalities in HEART RATE, disorders of electrical impulse generation, or impulse conduction.
Edrophonium
A rapid-onset, short-acting cholinesterase inhibitor used in cardiac arrhythmias and in the diagnosis of myasthenia gravis. It has also been used as an antidote to curare principles.
Cardiac Complexes, Premature
A group of cardiac arrhythmias in which the cardiac contractions are not initiated at the SINOATRIAL NODE. They include both atrial and ventricular premature beats, and are also known as extra or ectopic heartbeats. Their frequency is increased in heart diseases.
Anti-arrhythmia Agents
Agents used for the treatment or prevention of cardiac arrhythmias. They may affect the polarization-repolarization phase of the action potential, its excitability or refractoriness, or impulse conduction or membrane responsiveness within cardiac fibers. Anti-arrhythmia agents are often classed into four main groups according to their mechanism of action: sodium channel blockade, beta-adrenergic blockade, repolarization prolongation, or calcium channel blockade.
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