A case of disseminated intravascular coagulation associated with a prosthetic heart valve.
Summary of "A case of disseminated intravascular coagulation associated with a prosthetic heart valve."
Malfunctioning prosthetic heart valves have been previously associated with nonimmune hemolytic anemia; however, disseminated intravascular coagulation has not previously been noted as a complication in the absence of infective endocarditis. The authors report the case of an 81-year-old woman who developed disseminated intravascular coagulation associated with a dysfunctional prosthetic heart valve.
Affiliation
From the Division of Hematology/Oncology (ctc), Department of Medicine (ctc, ra, crm, cyc), The Texas A&M Health Science Center College of Medicine, Temple, Texas; and Scott and White Memorial Hospital System (ctc, crm, cyc), Temple, Texas.
Journal Details
This article was published in the following journal.
Name: The American journal of the medical sciences
ISSN: 1538-2990
Pages: 83-5
Links
- PubMed Source: http://www.ncbi.nlm.nih.gov/pubmed/21191264
- DOI: http://dx.doi.org/10.1097/MAJ.0b013e3181f7d7bd
Medical and Biotech [MESH] Definitions
Leukemia, Promyelocytic, Acute
An acute myeloid leukemia in which abnormal PROMYELOCYTES predominate. It is frequently associated with DISSEMINATED INTRAVASCULAR COAGULATION.
Gabexate
A serine proteinase inhibitor used therapeutically in the treatment of pancreatitis, disseminated intravascular coagulation (DIC), and as a regional anticoagulant for hemodialysis. The drug inhibits the hydrolytic effects of thrombin, plasmin, and kallikrein, but not of chymotrypsin and aprotinin.
Disseminated Intravascular Coagulation
A disorder characterized by procoagulant substances entering the general circulation causing a systemic thrombotic process. The activation of the clotting mechanism may arise from any of a number of disorders. A majority of the patients manifest skin lesions, sometimes leading to PURPURA FULMINANS.
Purpura Fulminans
A severe, rapidly fatal reaction occurring most commonly in children following an infectious illness. It is characterized by large, rapidly spreading skin hemorrhages, fever, or shock. Purpura fulminans often accompanies or is triggered by DISSEMINATED INTRAVASCULAR COAGULATION.
Exchange Transfusion, Whole Blood
Repetitive withdrawal of small amounts of blood and replacement with donor blood until a large proportion of the blood volume has been exchanged. Used in treatment of fetal erythroblastosis, hepatic coma, sickle cell anemia, disseminated intravascular coagulation, septicemia, burns, thrombotic thrombopenic purpura, and fulminant malaria.
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