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Malfunctioning prosthetic heart valves have been previously associated with nonimmune hemolytic anemia; however, disseminated intravascular coagulation has not previously been noted as a complication in the absence of infective endocarditis. The authors report the case of an 81-year-old woman who developed disseminated intravascular coagulation associated with a dysfunctional prosthetic heart valve.
From the Division of Hematology/Oncology (ctc), Department of Medicine (ctc, ra, crm, cyc), The Texas A&M Health Science Center College of Medicine, Temple, Texas; and Scott and White Memorial Hospital System (ctc, crm, cyc), Temple, Texas.
This article was published in the following journal.
Name: The American journal of the medical sciences
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A serine proteinase inhibitor used therapeutically in the treatment of pancreatitis, disseminated intravascular coagulation (DIC), and as a regional anticoagulant for hemodialysis. The drug inhibits the hydrolytic effects of thrombin, plasmin, and kallikrein, but not of chymotrypsin and aprotinin.
A disorder characterized by procoagulant substances entering the general circulation causing a systemic thrombotic process. The activation of the clotting mechanism may arise from any of a number of disorders. A majority of the patients manifest skin lesions, sometimes leading to PURPURA FULMINANS.
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Repetitive withdrawal of small amounts of blood and replacement with donor blood until a large proportion of the blood volume has been exchanged. Used in treatment of fetal erythroblastosis, hepatic coma, sickle cell anemia, disseminated intravascular coagulation, septicemia, burns, thrombotic thrombopenic purpura, and fulminant malaria.
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Cardiovascular disease (CVD)
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