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Seven New Monoterpenoid Indole Alkaloids from Gelsemium elegans.

06:00 EDT 21st October 2010 | BioPortfolio

Summary of "Seven New Monoterpenoid Indole Alkaloids from Gelsemium elegans."

Seven new indole alkaloids were isolated from the roots of Gelsemium elegans Benth. and their structures were determined by spectroscopic analysis and chemical transformation from known alkaloids. Kounaminal (1) is a new koumine-type alkaloid that contains an unusual aminal moiety. Humantenoxenine (2) and 15-hydroxyhumantenoxenine (3) are humantenine-type alkaloids that contain a novel β-amino-α,β-unsaturated ketone residue. The other four novel alkaloids are two gelsedilam-related and two gelsenicine-related alkaloids.

Affiliation

Graduate School of Pharmaceutical Sciences, Chiba University, 1-33 Yayoi-cho, Inage-ku, Chiba 263-8522 (Japan), Fax: (+81) 43-290-2901.

Journal Details

This article was published in the following journal.

Name: Chemistry, an Asian journal
ISSN: 1861-471X
Pages: 166-73

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Medical and Biotech [MESH] Definitions

Benzo-indoles similar to CARBOLINES which are pyrido-indoles. In plants, carbazoles are derived from indole and form some of the INDOLE ALKALOIDS.

Group of alkaloids containing a benzylpyrrole group (derived from TRYPTOPHAN)

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A plant genus of the family POLYGALACEAE that contains securiosides and indole alkaloids.

A plant genus of the family RUBIACEAE. Members contain psychotridine and brachycerine (indole alkaloids).

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