Adynamic Ileus Induced by Varenicline.
Summary of "Adynamic Ileus Induced by Varenicline."
Varenicline is a drug specifically developed for smoking cessation. Gastrointestinal symptoms are among the most common side effects (nausea, vomiting, and constipation). Here, we described the case of a 75 year-old man who suffered from functional adynamic ileus while taking varenicline. Adynamic ileus is a rare condition on treatment with varenicline. Clinicals should be aware of this side effect due to it could lead to varenicline withdrawal and reconsideration of patient smoking cessation strategy.
Affiliation
Internal Medicine department, University Hospital Ramón y Cajal, Colmenar Viejo Road km 9.1. ZP 28034, Madrid, Spain. pg_vasco@yahoo.es.
Journal Details
This article was published in the following journal.
Name: Current drug safety
ISSN: 1574-8863
Pages:
Links
- PubMed Source: http://www.ncbi.nlm.nih.gov/pubmed/21241240
- DOI: http://dx.doi.org/
Medical and Biotech [MESH] Definitions
Ileus
A condition caused by the lack of intestinal PERISTALSIS or INTESTINAL MOTILITY without any mechanical obstruction. This interference of the flow of INTESTINAL CONTENTS often leads to INTESTINAL OBSTRUCTION. Ileus may be classified into postoperative, inflammatory, metabolic, neurogenic, and drug-induced.
Hyperthermia, Induced
Abnormally high temperature intentionally induced in living things regionally or whole body. It is most often induced by radiation (heat waves, infra-red), ultrasound, or drugs.
Labor, Induced
Artificially induced UTERINE CONTRACTION. Generally, LABOR, OBSTETRIC is induced with the intent to cause delivery of the fetus and termination of pregnancy.
Intestinal Pseudo-obstruction
A type of ILEUS, a functional not mechanical obstruction of the INTESTINES. This syndrome is caused by a large number of disorders involving the smooth muscles (MUSCLE, SMOOTH) or the NERVOUS SYSTEM.
Gastric Dilatation
Abnormal distention of the STOMACH due to accumulation of gastric contents that may reach 10 to 15 liters. Gastric dilatation may be the result of GASTRIC OUTLET OBSTRUCTION; ILEUS; GASTROPARESIS; or denervation.
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