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Pemetrexed in Previously Treated Non-small Cell Lung Cancer Patients with Poor Performance Status.

09:51 EDT 19th May 2013 | BioPortfolio

Summary of "Pemetrexed in Previously Treated Non-small Cell Lung Cancer Patients with Poor Performance Status."

Pemetrexed have been approved for the treatment of patients affected by advanced non-small cell lung cancner (NSCLC) in progression after first-line chemotherapy. We evaluated the activity and feasibility of pemetrexed in previously treated NSCLC.

Affiliation

Department of Internal Medicine, Chungnam National University Hospital, Daejon, Korea.

Journal Details

This article was published in the following journal.

Name: Zhongguo fei ai za zhi = Chinese journal of lung cancer
ISSN: 1999-6187
Pages: 33-8

Links

Medical and Biotech [MESH] Definitions

Carcinoma, Bronchogenic

Malignant neoplasm arising from the epithelium of the BRONCHI. It represents a large group of epithelial lung malignancies which can be divided into two clinical groups: SMALL CELL LUNG CANCER and NON-SMALL-CELL LUNG CARCINOMA.

Small Cell Lung Carcinoma

A form of highly malignant lung cancer that is composed of small ovoid cells (SMALL CELL CARCINOMA).

Carcinoma, Non-small-cell Lung

A heterogeneous aggregate of at least three distinct histological types of lung cancer, including SQUAMOUS CELL CARCINOMA; ADENOCARCINOMA; and LARGE CELL CARCINOMA. They are dealt with collectively because of their shared treatment strategy.

Tumor Suppressor Protein P53

Nuclear phosphoprotein encoded by the p53 gene (GENES, P53) whose normal function is to control CELL PROLIFERATION and APOPTOSIS. A mutant or absent p53 protein has been found in LEUKEMIA; OSTEOSARCOMA; LUNG CANCER; and COLORECTAL CANCER.

Lung Neoplasms

Tumors or cancer of the LUNG.

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