The effect of botulinum toxin injection on the hang-back recession of rectus muscles.
Summary of "The effect of botulinum toxin injection on the hang-back recession of rectus muscles."
Hang-back recession and botulinum toxin injection are performed as one treatment option for the correction of large angles of deviation. However, the effect of botulinum toxin on hang-back recession has not been thoroughly evaluated. The purpose of this study is to investigate the effect of botulinum toxin on the hang-back recession of extraocular muscles.
Under general anesthesia, 6-mm hang-back recession of the superior rectus muscle (SR) was performed in all eyes of 12 rabbits. Botulinum toxin (5 IU, 0.1 ml) was injected into the SR of one eye in each rabbit. The inferior rectus muscles (IR) of both eyes were excised to model severe paralysis. The distance between the superior limbus and the new insertion was measured immediately after the procedure and 3 months postoperatively. Changes in the location of the insertion were evaluated and compared between both eyes.
After excision of the IR, upward deviation was observed in all eyes. The insertion site of the recessed SR immediately after the procedure and 3 months postoperatively were significantly different in all rabbit eyes with or without botulinum injection (P = 0.002, 0.002); SR advancement was observed in both cases. The amount of advancement was 1.38 ± 0.41 mm in the SR without botulinum toxin injection and 2.29 ± 0.45 mm in the SR with injection; this difference was statistically significant (P = 0.002).
Botulinum toxin injection reduced the amount of hang-back recession in deviated rabbit eyes. Surgeons should be aware that botulinum toxin can diminish the effects of hang-back recession when used simultaneously.
Department of Ophthalmology, Korea University College of Medicine, 126-1 5ga Anam-dong Sungbuk-gu, Seoul, 136-705, South Korea.
This article was published in the following journal.
- PubMed Source: http://www.ncbi.nlm.nih.gov/pubmed/21253757
- DOI: http://dx.doi.org/10.1007/s00417-011-1615-y
Medical and Biotech [MESH] Definitions
Clostridium Botulinum Type C
Subtype of CLOSTRIDIUM BOTULINUM that produces botulinum toxin type C which is neurotoxic to ANIMALS, especially CATTLE, but not humans. It causes dissociation of ACTIN FILAMENTS.
Clostridium Botulinum Type D
Subtype of CLOSTRIDIUM BOTULINUM that produces botulinum toxin type D which is neurotoxic to ANIMALS, especially CATTLE, but not humans.
Clostridium Botulinum Type F
Subtype of CLOSTRIDIUM BOTULINUM that produces botulinum toxin type F which is neurotoxic to humans and animals.
Clostridium Botulinum Type E
Subtype of CLOSTRIDIUM BOTULINUM that produces botulinum toxin type E which is neurotoxic to humans and animals.
Clostridium Botulinum Type B
Subtype of CLOSTRIDIUM BOTULINUM that produces botulinum toxin type B which is neurotoxic to humans and animals.
This report describes an inadvertent perforation of the globe while injecting botulinum toxin A into the medial rectus muscle without electromyography guidance. Botulinum toxin A does not appear to ha...
BACKGROUND: The myotendinous nerve endings located in the extraocular muscles are considered as proprioceptors. The proprioception of extraocular muscles can be altered if botuminium toxin, which is w...
PURPOSE:: We evaluated the comparative effects of intraprostatic injection of cobra cardiotoxin D and botulinum toxin type A on prostate structure in the rat model. MATERIALS AND METHODS:: A total of...
BACKGROUND: Pharyngoesophageal spasm is a known entity to cause hypertonic/failed tracheoesophageal speech and is successfully treated by botulinum toxin A injection. However, success of botulinum tox...
PURPOSE:To report an outcome study of 123 consecutive patients treated by graded unilateral medial rectus recession for small to moderate angle esotropia over an 8-year period with a minimum follow-up...
The purpose of this study is to evaluate the effectiveness of bilateral lateral rectus muscle recession versus unilateral lateral rectus recession with medial rectus resection procedures f...
This study will assess the efficacy and the duration of efficacy of Botulinum toxin A (Botox®) injected into the lumbar paraspinal muscles for reducing pain and disability in subjects suf...
According to high rate of vaginismus (about 10 percent) which leads to unconsummated marriage (about 1 percent) and low efficacy for conventional treatments such as biofeedback therapy, an...
Some studies valued the effectiveness of botulinum toxin. Results are contradictory and we need more studies. The purpose of the study is to compare the effectiveness of botulinum toxin i...
Botulism is a severe form of food poisoning caused by bacteria. This bacteria produces several toxins one of which is botulinum toxin A. This toxin causes the symptoms of food poisoning....