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Metabolic Syndrome, Androgens, and Hypertension.

06:00 EST 29th January 2011 | BioPortfolio

Summary of "Metabolic Syndrome, Androgens, and Hypertension."

Obesity is one of the constellation of factors that make up the definition of the metabolic syndrome. Metabolic syndrome is also associated with insulin resistance, dyslipidemia, hypertriglyceridemia, and type 2 diabetes mellitus. The presence of obesity and metabolic syndrome in men and women is also associated with increased risk of cardiovascular disease and hypertension. In men, obesity and metabolic syndrome are associated with reductions in testosterone levels. In women, obesity and metabolic syndrome are associated with increases in androgen levels. In men, reductions in androgen levels are associated with inflammation, and androgen supplements reduce inflammation. In women, increases in androgens are associated with increases in inflammatory cytokines, and reducing androgens reduces inflammation. This review discusses the possibility that the effects of androgens on metabolic syndrome and its sequelae may differ between males and females.

Affiliation

Women's Health Research Center, University of Mississippi Medical Center, 2500 N. State Street, Jackson, MS, 39216-4505, USA.

Journal Details

This article was published in the following journal.

Name: Current hypertension reports
ISSN: 1534-3111
Pages:

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