Principles of pharmacology.
Summary of "Principles of pharmacology."
An understanding of the basic principles of pharmacokinetics and pharmacodynamics of drugs is important in appropriate therapeutic use of various drugs. In simple terms, the effects of the body on the drug once it has entered the body has been referred to as pharmacokinetics, and it aims to provide a quantitative assessment of the main processes involved in biodisposition of the drug, including absorption, distribution, metabolism, and elimination. Pharmacodynamics concerns itself with the effects of the drug on the body and the main processes involved are the action of the drug on specific sites, especially the receptors. In addition, pharmacogenetics and pharmacogenomics evaluates the influence of genetics on drug response. This article reviews basic concepts of pharmacology applicable to psychotherapeutic agents used for the treatment of mental disorders of children and adolescents.
Borgess Ambulatory Care, 1701 Gull Road, Kalamazoo, MI 49048, USA; Department of Pharmacy Practice, Ferris State University College of Pharmacy, Big Rapids, MI 49307, USA.
This article was published in the following journal.
Name: Pediatric clinics of North America
- PubMed Source: http://www.ncbi.nlm.nih.gov/pubmed/21281845
- DOI: http://dx.doi.org/10.1016/j.pcl.2010.10.005
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Scott Waldman is currently the Chairman of the Department of Pharmacology and Experimental Therapeutics and the Director of the Division of Clinical Pharmacology. He is the Samuel MV Professor, Depart...
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Medical and Biotech [MESH] Definitions
The branch of pharmacology that deals directly with the effectiveness and safety of drugs in humans.
The branch of pharmacology dealing especially with the action of drugs upon various parts of the nervous system.
The study of the origin, nature, properties, and actions of drugs and their effects on living organisms.
The scientific disciplines concerned with the embryology, anatomy, physiology, biochemistry, pharmacology, etc., of the nervous system.
A phenylacetamide that was formerly used in ANALGESICS but nephropathy and METHEMOGLOBINEMIA led to its withdrawal from the market. (From Smith and Reynard, Textbook of Pharmacology,1991, p431)