Principles of pharmacology.
Summary of "Principles of pharmacology."
An understanding of the basic principles of pharmacokinetics and pharmacodynamics of drugs is important in appropriate therapeutic use of various drugs. In simple terms, the effects of the body on the drug once it has entered the body has been referred to as pharmacokinetics, and it aims to provide a quantitative assessment of the main processes involved in biodisposition of the drug, including absorption, distribution, metabolism, and elimination. Pharmacodynamics concerns itself with the effects of the drug on the body and the main processes involved are the action of the drug on specific sites, especially the receptors. In addition, pharmacogenetics and pharmacogenomics evaluates the influence of genetics on drug response. This article reviews basic concepts of pharmacology applicable to psychotherapeutic agents used for the treatment of mental disorders of children and adolescents.
Borgess Ambulatory Care, 1701 Gull Road, Kalamazoo, MI 49048, USA; Department of Pharmacy Practice, Ferris State University College of Pharmacy, Big Rapids, MI 49307, USA.
This article was published in the following journal.
Name: Pediatric clinics of North America
- PubMed Source: http://www.ncbi.nlm.nih.gov/pubmed/21281845
- DOI: http://dx.doi.org/10.1016/j.pcl.2010.10.005
Ipilimumab is a fully human, monoclonal antibody that blocks cytotoxic T-lymphocyte antigen-4. The objective of the present study was to characterize the clinical pharmacology profile of ipilimumab us...
Scott Waldman is currently the Chairman of the Department of Pharmacology and Experimental Therapeutics and the Director of the Division of Clinical Pharmacology. He is the Samuel MV Professor, Depart...
This study was conducted to evaluate potential pharmacokinetic interactions between docetaxel and atrasentan as part of a phase I/II clinical trial.
We are examining the pharmacology of 17-OHPC in pregnancy, specifically between the second and third trimesters.
Sarpogrelate is an antiplatelet agent that decreases 5-hydroxytryptamine( 5-HT )levels in platelets via blockade of 5-HT2 receptors, has been used in atherosclerotic peripheral arterial di...
To determine the overall response rate to liposomal 9-Nitro-20 (S)-Camptothecin (L9NC) administered by aerosolization in patients with non-small-cell lung cancer (any stage). To determine...
The purpose of this study is to investigate the pharmacological effects of MDA in healthy humans.
This is a phase I and pharmacology study of Camptothecin-20-O-Propionate Hydrate (CZ48) in Patients with Solid Tumors or Lymphoma. OBJECTIVES Primary: 1. To describe the d...
Medical and Biotech [MESH] Definitions
The branch of pharmacology that deals directly with the effectiveness and safety of drugs in humans.
The branch of pharmacology dealing especially with the action of drugs upon various parts of the nervous system.
The study of the origin, nature, properties, and actions of drugs and their effects on living organisms.
The scientific disciplines concerned with the embryology, anatomy, physiology, biochemistry, pharmacology, etc., of the nervous system.
A phenylacetamide that was formerly used in ANALGESICS but nephropathy and METHEMOGLOBINEMIA led to its withdrawal from the market. (From Smith and Reynard, Textbook of Pharmacology,1991, p431)