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Toxic metal contamination was investigated in Artemisia annua L. herbal preparations from different commercial sources in China. Measurable amounts of copper (Cu), lead (Pb), arsenic (As), mercury (Hg), cadmium (Cd), chromium (Cr), manganese (Mn), nickel (Ni) and aluminium (Al) were detected in commercial dried Artemisia annua L., Massa Medicata Fermentata (Shenqu), Semen Sojae Praeparatum, medicated leaven (Jianqu) and an oral dose of Zhongganling-pian by inductively coupled plasma optical emission spectrometry (ICP-OES) and atomic fluorescence spectrometry (AFS). A total of 69 samples were collected from different sources in the Chinese market. Toxic metals contents in the investigated samples were found at different levels. Results showed that 94.20, 100, 97.10, 91.30 and 94.20% of the products fully complied with the quality requirement for traditional medicines in China pertaining to Cu, Pb, As, Hg and Cd, respectively. Although toxic metal concentrations measured in this study do not pose a serious health risk, they do affect the quality of herbal preparations. Moreover, on the basis of the results obtained in the present work, it is concluded that the present techniques are suitable for the routine determination of toxic metals concentration in various pharmaceutical dosage forms.
Institute of Medicinal Plant Development, Chinese Academy of Medical Sciences, Peking Union Medical College, Beijing, 100193, China.
This article was published in the following journal.
Name: Journal of natural medicines
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A plant species of the genus ARTEMISIA, family ASTERACEAE. It is the source of the antimalarial artemisinin (ANTIMALARIALS).
A plant species of the genus ARTEMISIA, family ASTERACEAE that has been used in ABSINTHE. The oil contains neurotoxic 1-thujone and d-isothujone.
Anthelmintic isolated from the dried unexpanded flower heads of Artemisia maritima and other species of Artemisia found principally in Russian and Chinese Turkestan and the Southern Ural region. (From Merck, 11th ed.)
A genus of trees in the VERBENACEAE (sometimes classified in the LAMIACEAE) family containing assorted flavonoids with possible analgesic and antineoplastic properties. The fruit of these trees is used in herbal preparations.
Objects of precious metal usually containing gems and worn to enhance personal appearance. Health concerns include possible contamination from lead content or bacteria.
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