Molecular biology. The eukaryotic ribosome.
Summary of "Molecular biology. The eukaryotic ribosome."
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Affiliation
MRC Laboratory of Molecular Biology, Cambridge CB2 0QH, UK. ramak@mrc-lmb.cam.ac.uk
Journal Details
This article was published in the following journal.
Name: Science (New York, N.Y.)
ISSN: 1095-9203
Pages: 681-2
Links
- PubMed Source: http://www.ncbi.nlm.nih.gov/pubmed/21310988
- DOI: http://dx.doi.org/10.1126/science.1202093
Medical and Biotech [MESH] Definitions
Glyoxysomes
Microbodies which occur in plant cells, and in some eukaryotic microorganisms, and which contain enzymes of the glyoxylate cycle. (Singleton and Stainsbury, Dictionary of Microbiology and Molecular Biology, 2nd ed)
Ribosome Subunits
The two dissimilar sized ribonucleoprotein complexes that comprise a RIBOSOME - the large ribosomal subunit and the small ribosomal subunit. The eukaryotic 80S ribosome is composed of a 60S large subunit and a 40S small subunit. The bacterial 70S ribosome is composed of a 50S large subunit and a 30S small subunit.
Ribosome Subunits, Small, Eukaryotic
The small subunit of the 80s ribosome of eukaryotes. It is composed of the 18S RIBOSOMAL RNA and 32 different RIBOSOMAL PROTEINS.
Chromosomes
In a prokaryotic cell or in the nucleus of a eukaryotic cell, a structure consisting of or containing DNA which carries the genetic information essential to the cell. (From Singleton & Sainsbury, Dictionary of Microbiology and Molecular Biology, 2d ed)
Ribosome Subunits, Large, Eukaryotic
The large subunit of the 80s ribosome of eukaryotes. It is composed of the 28S RIBOSOMAL RNA, the 5.8S RIBOSOMAL RNA, the 5S RIBOSOMAL RNA, and about 50 different RIBOSOMAL PROTEINS.
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One core, two shells: bacterial and eukaryotic ribosomes.
Ribosomes are universally conserved enzymes that carry out protein biosynthesis. Bacterial and eukaryotic ribosomes, which share an evolutionarily conserved core, are thought to have evolved from a co...
Translation of mRNA into proteins by the ribosome is universally conserved in all cellular life. The composition and complexity of the translation machinery differ markedly between the three domains o...
Crystal structure of the eukaryotic 60S ribosomal subunit in complex with initiation factor 6.
Protein synthesis in all organisms is catalyzed by ribosomes. In comparison to their prokaryotic counterparts, eukaryotic ribosomes are considerably larger and are subject to more complex regulation....
Las1L is a nucleolar protein required for cell proliferation and ribosome biogenesis.
Ribosome biogenesis is a highly regulated process ensuring that cell growth (increase in biomass) is coordinated with cell proliferation. The formation of eukaryotic ribosomes is a multistep process i...
Eukaryotic translation requires a suite of proteins known as eukaryotic initiation factors (eIFs). These molecular effectors oversee the highly regulated initiation phase of translation. Essential to...
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