Respiratory system at high altitude: pathophysiology and novel therapy options.
Summary of "Respiratory system at high altitude: pathophysiology and novel therapy options."
This mini-review conveys information on lung function in hypoxia. Included are presentations of shape and layering of the atmosphere, physiologic basics of lung function at high altitude, pathophysiology of high altitude pulmonary edema (HAPE) and of current and potential therapy approaches for HAPE.
Section of Respiratory and Altitude Medicine, Medizinische Universität Innsbruck, Innsbruck, Austria.
This article was published in the following journal.
Name: Wiener klinische Wochenschrift
- PubMed Source: http://www.ncbi.nlm.nih.gov/pubmed/21318740
- DOI: http://dx.doi.org/10.1007/s00508-010-1501-3
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Exposure of healthy subjects to high altitude hypoxia elicits changes in cardiovascular, respiratory and metabolic features as weel as in exercise performance similar, for some aspects, to...
Based on the findings of decreased vital capacity, decreased FEV1 and increased closing volume after ascent to high altitude, some investigators suggest the presence of a subclinical high...
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The purpose of this study is to determine whether regular oral use of sildenafil citrate can prevent or attenuate high altitude illnesses.
Medical and Biotech [MESH] Definitions
A morbid condition of ANOXIA caused by the reduced available oxygen at high altitudes.
Respiratory support system used primarily with rates of about 100 to 200/min with volumes of from about one to three times predicted anatomic dead space. Used to treat respiratory failure and maintain ventilation under severe circumstances.
Care of patients with deficiencies and abnormalities associated with the cardiopulmonary system. It includes the therapeutic use of medical gases and their administrative apparatus, environmental control systems, humidification, aerosols, ventilatory support, bronchopulmonary drainage and exercise, respiratory rehabilitation, assistance with cardiopulmonary resuscitation, and maintenance of natural, artificial, and mechanical airways.
Functional processes and properties characteristic of the BLOOD; CARDIOVASCULAR SYSTEM; and RESPIRATORY SYSTEM.
Respiratory system manifestations of diseases of the respiratory tract or of other organs.