ATM Signals miRNA Biogenesis through KSRP.
Summary of "ATM Signals miRNA Biogenesis through KSRP."
In this issue of Molecular Cell, Zhang and colleagues (Zhang et al., 2011) describe a critical link between the DNA damage response and the miRNA pathway, in which DNA double-strand breaks (DSBs) induce ATM-dependent KSRP phosphorylation to facilitate pri-miRNA processing.
Department of Biochemistry, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA.
This article was published in the following journal.
Name: Molecular cell
- PubMed Source: http://www.ncbi.nlm.nih.gov/pubmed/21329874
- DOI: http://dx.doi.org/10.1016/j.molcel.2011.01.027
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