Ectopic ACTH-secreting neuroendocrine tumor.

18:25 EDT 23rd September 2014 | BioPortfolio

Summary of "Ectopic ACTH-secreting neuroendocrine tumor."

The authors report a case of an ectopic ACTH-syndrome that resulted in severe hypercortisolism, hypokalemia, diabetes mellitus and osteoporosis. The ACTH-secreting tumor tissue was localized in the lung. The tumor was removed by segmentectomy and histological evaluation revealed an ACTH-secreting neuroendocrine tumor. After surgery, however, plasma cortisol and ACTH levels failed to decrease significantly due to subtotal tumor removal. Long-acting somatostatin analogue therapy resulted in a normalization of both plasma cortisol and ACTH levels and the clinical symptoms improved significantly. Residual tumor was removed by repeat surgery and the patient was permanently cured. Orv. Hetil., 2011, 152, 403-406.

Affiliation

Borsod-Abaúj-Zemplén Megyei Kórház és Egyetemi Oktató Kórház II. Belgyógyászat Miskolc.

Journal Details

This article was published in the following journal.

Name: Orvosi hetilap
ISSN: 0030-6002
Pages: 403-406

Links

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Medical and Biotech [MESH] Definitions

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