Pediatric Vascular Malformations: Pathophysiology, Diagnosis, and the Role of Interventional Radiology.
Summary of "Pediatric Vascular Malformations: Pathophysiology, Diagnosis, and the Role of Interventional Radiology."
The Mulliken and Glowacki classification (1982) differentiated vascular anomalies into two groups based on their endothelial characteristics: hemangiomas and vascular malformations. Vascular anomalies are localized defects of the vasculature that affect a limited number of vessels in a restricted area of the body. These defects are secondary to errors in vascular morphogenesis. Depending on the type of vessel involved, the vascular malformation group was subdivided into high-flow (such as arteriovenous malformation and arteriovenous fistula) and low-flow lesions (such as venous and lymphatic malformations). Depending on the type of lesion, the location and degree of involvement and the clinical effect, different types of treatment would be required. For the purpose of this review, we concentrate solely on vascular malformations: the clinical features, genetics, diagnosis, and current treatment options.
Affiliation
Department of Interventional Radiology, Children's Hospital of Philadelphia, 34th Street and Civic Center Boulevard, Philadelphia, PA, 19104, USA, cahill@email.chop.edu.
Journal Details
This article was published in the following journal.
Name: Cardiovascular and interventional radiology
ISSN: 1432-086X
Pages:
Links
- PubMed Source: http://www.ncbi.nlm.nih.gov/pubmed/21409475
- DOI: http://dx.doi.org/10.1007/s00270-011-0123-0
Medical and Biotech [MESH] Definitions
Radiology, Interventional
Subspecialty of radiology that combines organ system radiography, catheter techniques and sectional imaging.
Endovascular Procedures
Minimally invasive procedures, diagnostic or therapeutic, performed within the BLOOD VESSELS. They may be perfomed via ANGIOSCOPY; INTERVENTIONAL MAGNETIC RESONANCE IMAGING; INTERVENTIONAL RADIOGRAPHY; or INTERVENTIONAL ULTRASONOGRAPHY.
Vascular Malformations
A spectrum of congenital, inherited, or acquired abnormalities in BLOOD VESSELS that can adversely affect the normal blood flow in ARTERIES or VEINS. Most are congenital defects such as abnormal communications between blood vessels (fistula), shunting of arterial blood directly into veins bypassing the CAPILLARIES (arteriovenous malformations), formation of large dilated blood blood-filled vessels (cavernous angioma), and swollen capillaries (capillary telangiectases). In rare cases, vascular malformations can result from trauma or diseases.
Vascular Headaches
Secondary headache disorders attributed to a variety of cranial or cervical vascular disorders, such as BRAIN ISCHEMIA; INTRACRANIAL HEMORRHAGES; and CENTRAL NERVOUS SYSTEM VASCULAR MALFORMATIONS.
Radiology
A specialty concerned with the use of x-ray and other forms of radiant energy in the diagnosis and treatment of disease.
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