Intramolecular Michael addition reaction for the synthesis of benzylbutyrolactones.

Summary of "Intramolecular Michael addition reaction for the synthesis of benzylbutyrolactones."

A convenient synthesis of benzyl-gamma-butyrolactone derivatives via intramolecular Michael addition reaction of nitro-substituted aryl allyl beta-ketocarboxylates is reported. The method features simple operation, mild reaction conditions and high efficiency.


State Key Laboratory of Organometallic Chemistry, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, 345 Lingling Lu, Shanghai, 200032, P. R. China.

Journal Details

This article was published in the following journal.

Name: Organic & biomolecular chemistry
ISSN: 1477-0539
Pages: 3207-10


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