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An unusual presentation of sarcoidosis with tetraplegia and severe osteolytic bone lesions.

06:00 EDT 2nd April 2011 | BioPortfolio

Summary of "An unusual presentation of sarcoidosis with tetraplegia and severe osteolytic bone lesions."

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Affiliation

Aarhus University Hospital, Dept of Respiratory Medicine, Norrebrogade 44, Aarhus, 8000 C, Denmark. E-mail: charhyld@rm.dk.

Journal Details

This article was published in the following journal.

Name: The European respiratory journal : official journal of the European Society for Clinical Respiratory Physiology
ISSN: 1399-3003
Pages: 964-6

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Medical and Biotech [MESH] Definitions

Sarcoidosis affecting predominantly the lungs, the site most frequently involved and most commonly causing morbidity and mortality in sarcoidosis. Pulmonary sarcoidosis is characterized by sharply circumscribed granulomas in the alveolar, bronchial, and vascular walls, composed of tightly packed cells derived from the mononuclear phagocyte system. The clinical symptoms when present are dyspnea upon exertion, nonproductive cough, and wheezing. (Cecil Textbook of Medicine, 19th ed, p431)

A extremely rare bone tumor characterized by abundant collagen formation and a fibrous stroma, without evidence of mitosis or pleomorphism. It appears on x-rays as an osteolytic lesion with well-defined margins and must be differentiated from primary fibrosarcoma of bone. (DeVita Jr et al., Cancer: Principles & Practice of Oncology, 3d ed, p1441)

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