Influence of blood pressure on cardio-ankle vascular index (CAVI) examined based on percentage change during general anesthesia.
Summary of "Influence of blood pressure on cardio-ankle vascular index (CAVI) examined based on percentage change during general anesthesia."
Cardio-ankle vascular index (CAVI) and brachial-ankle pulse wave velocity (baPWV) are non-invasive methods for estimating arterial distensibility. The purpose of this study is to evaluate whether CAVI as an index of true arterial stiffness is superior to baPWV based on the percentage change in hemodynamics under general anesthesia. CAVI (segment from heart to ankle), k-CAVI (heart to knee) and baPWV (brachial to ankle) in 30 oral surgery patients were measured to compare the decreased blood pressure (BP) after 10 min of tracheal intubation during general anesthesia with the control BP (after 5 min of rest). General anesthesia was performed under endotracheal intubation through intravenous injection of propofol, fentanyl and vecuronium or rocuronium. In both the elderly (65 years) and middle-aged (<65 years) groups, CAVI and k-CAVI did not change during general anesthesia, whereas baPWV and systolic BP (SBP) showed a statistically significant decrease. Thus, the changes in CAVI (ΔCAVI) and k-CAVI (Δk-CAVI) showed no significant correlations with those of SBP (ΔSBP), whereas the changes in baPWV (ΔbaPWV) were significantly correlated with ΔSBP. ΔCAVI and Δk-CAVI showed no significant differences between the two groups, whereas ΔbaPWV and ΔSBP in the elderly group was much higher than that in the middle-aged group. Measurement of CAVI was not affected by the decrease in BP during general anesthesia. In contrast, baPWV was significantly influenced by changes in BP. These findings suggest that CAVI is a useful index of true arterial stiffness and is superior to baPWV.Hypertension Research advance online publication, 7 April 2011; doi:10.1038/hr.2011.31.
Affiliation
Department of Dental Anesthesiology, Nihon University School of Dentistry, Tokyo, Japan.
Journal Details
This article was published in the following journal.
Name: Hypertension research : official journal of the Japanese Society of Hypertension
ISSN: 1348-4214
Pages:
Links
- PubMed Source: http://www.ncbi.nlm.nih.gov/pubmed/21471974
- DOI: http://dx.doi.org/10.1038/hr.2011.31
Medical and Biotech [MESH] Definitions
Ankle Brachial Index
Comparison of the BLOOD PRESSURE between the BRACHIAL ARTERY and the POSTERIOR TIBIAL ARTERY. It is a predictor of PERIPHERAL ARTERIAL DISEASE.
Vascular Resistance
The force that opposes the flow of BLOOD through a vascular bed. It is equal to the difference in BLOOD PRESSURE across the vascular bed divided by the CARDIAC OUTPUT.
Vascular Capacitance
The measure of a BLOOD VESSEL's ability to increase the volume of BLOOD it holds without a large increase in BLOOD PRESSURE. The vascular capacitance is equal to the change in volume divided by the change in pressure.
Baroreflex
A response by the BARORECEPTORS to increased BLOOD PRESSURE. Increased pressure stretches BLOOD VESSELS which activates the baroreceptors in the vessel walls. The net response of the CENTRAL NERVOUS SYSTEM is a reduction of central sympathetic outflow. This reduces blood pressure both by decreasing peripheral VASCULAR RESISTANCE and by lowering CARDIAC OUTPUT. Because the baroreceptors are tonically active, the baroreflex can compensate rapidly for both increases and decreases in blood pressure.
Ankle Injuries
Harm or hurt to the ankle or ankle joint usually inflicted by an external source.
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