Dentin bond strength of an experimental adhesive system containing calcium chloride, synthetic peptides derived from dentin matrix protein 1 (pA and pB), and hydroxyapatite for direct pulp capping and as a bonding agent.

05:56 EST 30th January 2015 | BioPortfolio

Summary of "Dentin bond strength of an experimental adhesive system containing calcium chloride, synthetic peptides derived from dentin matrix protein 1 (pA and pB), and hydroxyapatite for direct pulp capping and as a bonding agent."

The purpose of this study was to evaluate the microtensile bond strength (muTBS) of an experimental adhesive system containing calcium chloride (CaCl(2)), synthetic peptides derived from dentin matrix protein 1 (DMP1: pA and pB), and hydroxyapatite experimentally developed for direct pulp capping to human dentin. Clearfil SE Bond/Primer (SEP) and Bond (SEB) were used for each experimental group as the matrix agents. Experimental self-etching primers included: primer-I, SEP containing 10 wt% CaCl(2), and primer-II, SEP containing a 10 wt% compound of pA and pB. The experimental bonding agent was a mixture of SEB and 10 wt% hydroxyapatite. Specimens were divided into five experimental groups, including the control, according to the mode of primer application. Primer-I was primarily applied, followed by primer-II for group 1, primer-I as the primary and SEP as the secondary for group 2, SEP as the primary and primer-II as the secondary for group 3, and SEP was applied twice for group 4, and SEP was applied once for the control. Clearfil SE Bond adhesive system was used as the control. Flat dentin surfaces of human molars were assigned to bonding tests. After each experimental primer was applied to the dentin surface, each experimental bonding agent was applied and photopolymerized, and then resin composite paste (Clearfil Flow FX and Clearfil AP-X) was placed and photopolymerized. The specimens were subjected to muTBS testing. The data were compared using analysis of variance (ANOVA) and post-hoc Bonferroni/Dunn tests. Results showed that the minimum mean value of muTBS was 15.4 MPa for group 1, while the maximum mean value of muTBS was 52.7 MPa for the control. There were significant differences among the experimental groups, except for group 4 and the control. The experimental primers containing CaCl(2) or DMP1 negatively affected the muTBS value of the experimental adhesive system to dentin.


Department of Operative Dentistry, The Nippon Dental University School of Life Dentistry at Niigata, 1-8 Hamaura-cho, Chuo-ku, Niigata, 951-8580, Japan,

Journal Details

This article was published in the following journal.

Name: Odontology / the Society of the Nippon Dental University
ISSN: 1618-1255
Pages: 110-6


PubMed Articles [20733 Associated PubMed Articles listed on BioPortfolio]

Comparison of bond strength of self-etch adhesive to pulp chamber dentin after placement of calcium hydroxide and various antibiotic pastes.

Abstract Objective. The aim of this study was to evaluate the effect of calcium hydroxide, double antibiotic paste (DAP) and triple antibiotic paste (TAP) with minocycline, cefaclor and amoxicillin on...

Effect of calcium hydroxide dressing on push-out bond strength of endodontic sealers to root canal dentin.

The aim of the present study was to evaluate the effect of calcium hydroxide dressing on the bond strength of three commercially available endodontic sealers (MTA Fillapex, Sealapex, and AH Plus) to r...

Evaluation of pH, ultimate tensile strength, and micro-shear bond strength of two self-adhesive resin cements.

The aim of this study was to evaluate the pH, ultimate tensile strength (UTS), and micro-shear bond strength (µSBS) of two self-adhesive resin cements to enamel and dentin. Sound bovine incisors (n =...

The effect of dentin desensitizers and Nd:YAG laser pre-treatment on microtensile bond strength of self-adhesive resin cement to dentin.

The purpose of this study is to evaluate if pre-treatment with desensitizers have a negative effect on microtensile bond strength before cementing a restoration using recently introduced self-adhesive...

Use of methacrylate-modified chitosan to increase the durability of dentin bonding systems.

This study aimed at investigating the effect of a methacrylate-modified chitosan on the durability of adhesive interfaces to improve the clinical performance of dental restorations. Chitosan was modif...

Clinical Trials [3204 Associated Clinical Trials listed on BioPortfolio]

Clinical Evaluation of Three Dental Adhesive Systems in Class V Restorations

The purpose of this study is to compare the clinical performance of three dental adhesive systems used to bond Class V cavity fillings in adult teeth.

Closure Techniques and Scar Appearance

The goal of this study is to assess whether wound closure with skin adhesive or running stitches combined with skin adhesive will be superior to standard wound sutures. This is a split-wou...

Validation of Brief Objective Neurobehavioral Detectors (BOND) in Mild TBI

The Veterans Health Administration (VHA) has stated the need for a brief screening instrument that can assist with the triage of the enormous number of returning OEF/OIF veterans with conc...

Clinical Evaluation Of A New Two-Component Self-Etch Universal Adhesive

This randomized clinical trial evaluates the clinical performance of a new two-component self-etch universal adhesive, OptiBond XTR, when applied in non-carious Class V cervical lesions wi...

Evaluation of Adhesion Quality and Irritation of an Alternate Second Generation Estradiol Transdermal System

The primary objective of this study was to compare the adhesive quality of the current Mylan estradiol placebo transdermal system, with that of an alternate second generation Mylan estradi...

Medical and Biotech [MESH] Definitions

Cements that act through infiltration and polymerization within the dentinal matrix and are used for dental restoration. They can be adhesive resins themselves, adhesion-promoting monomers, or polymerization initiators that act in concert with other agents to form a dentin-bonding system.

Adherent debris produced when cutting the enamel or dentin in cavity preparation. It is about 1 micron thick and its composition reflects the underlying dentin, although different quantities and qualities of smear layer can be produced by the various instrumentation techniques. Its function is presumed to be protective, as it lowers dentin permeability. However, it masks the underlying dentin and interferes with attempts to bond dental material to the dentin.

An autologous or commercial tissue adhesive containing FIBRINOGEN and THROMBIN. The commercial product is a two component system from human plasma that contains more than fibrinogen and thrombin. The first component contains highly concentrated fibrinogen, FACTOR VIII, fibronectin, and traces of other plasma proteins. The second component contains thrombin, calcium chloride, and antifibrinolytic agents such as APROTININ. Mixing of the two components promotes BLOOD CLOTTING and the formation and cross-linking of fibrin. The tissue adhesive is used for tissue sealing, HEMOSTASIS, and WOUND HEALING.

Adhesive tape with the mechanical strength to resist stretching. It is applied to the skin to support, stabilize, and restrict movement to aid healing and/or prevent injuries of MUSCULOSKELETAL SYSTEM.


Search BioPortfolio:

Relevant Topic

Latest News Clinical Trials Research Drugs Reports Corporate
Dentistry is the study, management and treatment of diseases and conditions affecting the mouth, jaw, teeth and their supporting tissues (Oxford Medical Dictionary) The work of a dentist ranges from regular patient check-up to orthodontics and surgery....