Investigation of the Change of Quality of Life and Depression in Lung Cancer Patients before and after Chemotherapy.
Summary of "Investigation of the Change of Quality of Life and Depression in Lung Cancer Patients before and after Chemotherapy."
BACKGROUND:
Quality of life (QoL) is an important end point in cancer patients, and depressive symptoms are significantly more frequent in lung cancer patients. The aim of this study is to observe the impact of chemotherapy on quality of life and emotion among lung cancer patients.
METHODS:
Fourty lung cancer patients were assessed with clinical outcomes, the EORTC QLQ-C30, SDS questionnaires before chemotherapy, one week after 2 cycles of chemotherapy, one week after 4 cycles of chemotherapy.
RESULTS:
Before chemotherapy, the scores of functioning scales were high, the rate of depression was 65%. After 2 cycles of chemotherapy, effective rate was 42.5%, the scores of cognitive function increase, the scores of role, emotional, social function decrease, the scores of dyspnoea decrease, the scores of pain, appetite loss, insomnia, constipation, diarrhea increase, the scores of Global quality of life decrease; the rate of depression was 70%. After 4 cycles of chemotherapy, effective rate was 23%, the scores of physical, role, emotional, social function decrease, the scores of symptom scales increase, the scores of dyspnoea, nausea and vomiting, appetite loss, financial impact increase, the scores of global quality of life decrease, the rate of depression was 87.5%.
CONCLUSIONS:
Some patients have symptoms relieved, but during the chemotherapy, the patients have significant depression, the quality of life decrease. We should evaluate the quality of life and emotions of lung cancer patients, and give positive psychological intervention to improve the quality of life.
Affiliation
Graduate School, Tianjin Medical University, Tianjin 300070, China.
Journal Details
This article was published in the following journal.
Name: Zhongguo fei ai za zhi = Chinese journal of lung cancer
ISSN: 1999-6187
Pages: 358-361
Links
- PubMed Source: http://www.ncbi.nlm.nih.gov/pubmed/21496436
- DOI: http://dx.doi.org/10.3779/j.issn.1009-3419.2011.04.10
Medical and Biotech [MESH] Definitions
Lung Compliance
The capability of the LUNGS to distend under pressure as measured by pulmonary volume change per unit pressure change. While not a complete description of the pressure-volume properties of the lung, it is nevertheless useful in practice as a measure of the comparative stiffness of the lung. (From Best & Taylor's Physiological Basis of Medical Practice, 12th ed, p562)
Quality-adjusted Life Years
A measurement index derived from a modification of standard life-table procedures and designed to take account of the quality as well as the duration of survival. This index can be used in assessing the outcome of health care procedures or services. (BIOETHICS Thesaurus, 1994)
National Institute Of Nursing Research (u.s.)
Component of the NATIONAL INSTITUTES OF HEALTH. It conducts and supports clinical and basic research to establish a scientific basis for the care of individuals across the life span, from the management of patients during illness and recovery to the reduction of risks for disease and disability; the promotion of healthy lifestyles; the promotion of quality of life in those with chronic illness; and the care for individuals at the end of life. It was established in 1986.
Quality Of Life
A generic concept reflecting concern with the modification and enhancement of life attributes, e.g., physical, political, moral and social environment; the overall condition of a human life.
Life Change Events
Those occurrences, including social, psychological, and environmental, which require an adjustment or effect a change in an individual's pattern of living.
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