Two case reports of Clostridium difficile bacteremia, one with the epidemic NAP-1 strain.
Summary of "Two case reports of Clostridium difficile bacteremia, one with the epidemic NAP-1 strain."
Clostridium difficile bacteremia is rare. Here, we report two cases of C. difficile bacteremia in patients with significant underlying gastrointestinal pathology. In one case, the bacteremia was caused by the North American pulsed-field gel electrophoresis (PFGE) type 1 (NAP-1) strain, which is responsible for recent outbreaks of C. difficile infections of increased severity.
Affiliation
Clinical Microbiology, Department of Pathology, The Ohio State University Medical Center, University Hospitals East, 1492 E. Broad Street, Columbus, OH, 43205, USA.
Journal Details
This article was published in the following journal.
Name: Infection
ISSN: 1439-0973
Pages:
Links
- PubMed Source: http://www.ncbi.nlm.nih.gov/pubmed/21509425
- DOI: http://dx.doi.org/10.1007/s15010-011-0115-7
Medical and Biotech [MESH] Definitions
Clostridium Difficile
A common inhabitant of the colon flora in human infants and sometimes in adults. It produces a toxin that causes pseudomembranous enterocolitis (ENTEROCOLITIS, PSEUDOMEMBRANOUS) in patients receiving antibiotic therapy.
Case Reports
Clinical presentations that may be followed by evaluative studies that eventually lead to a diagnosis.
Clostridium Tertium
A species of gram-positive bacteria in the family Clostridiaceae, causing BACTEREMIA in humans and ANIMALS.
Enterocolitis, Pseudomembranous
An acute inflammation of the INTESTINAL MUCOSA that is characterized by the presence of pseudomembranes or plaques in the SMALL INTESTINE (pseudomembranous enteritis) and the LARGE INTESTINE (pseudomembranous colitis). It is commonly associated with antibiotic therapy and CLOSTRIDIUM DIFFICILE colonization.
Immunity, Herd
The non-susceptibility to infection of a large group of individuals in a population. A variety of factors can be responsible for herd immunity and this gives rise to the different definitions used in the literature. Most commonly, herd immunity refers to the case when, if most of the population is immune, infection of a single individual will not cause an epidemic. Also, in such immunized populations, susceptible individuals are not likely to become infected. Herd immunity can also refer to the case when unprotected individuals fail to contract a disease because the infecting organism has been banished from the population.
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