Thymoma With Pure Red Cell Aplasia and Good's Syndrome.
Summary of "Thymoma With Pure Red Cell Aplasia and Good's Syndrome."
Thymoma patients with pure red cell aplasia (PRCA) or hypogammaglobulinemia (Good's syndrome) are rare, whereas those with both PRCA and Good's syndrome are even rarer. Here we present the case report of a 70-year-old woman with invasive thymoma and simultaneous PRCA and Good's syndrome, who achieved complete PRCA remission after thymectomy.
Affiliation
Journal Details
This article was published in the following journal.
Name: The Annals of thoracic surgery
ISSN: 1552-6259
Pages: 1620-2
Links
- PubMed Source: http://www.ncbi.nlm.nih.gov/pubmed/21524480
- DOI: http://dx.doi.org/10.1016/j.athoracsur.2010.10.010
Medical and Biotech [MESH] Definitions
Red-cell Aplasia, Pure
Suppression of erythropoiesis with little or no abnormality of leukocyte or platelet production.
Thymoma
A neoplasm originating from thymic tissue, usually benign, and frequently encapsulated. Although it is occasionally invasive, metastases are extremely rare. It consists of any type of thymic epithelial cell as well as lymphocytes that are usually abundant. Malignant lymphomas that involve the thymus, e.g., lymphosarcoma, Hodgkin's disease (previously termed granulomatous thymoma), should not be regarded as thymoma. (From Stedman, 25th ed)
Mobius Syndrome
A syndrome of congenital facial paralysis, frequently associated with abducens palsy and other congenital abnormalities including lingual palsy, clubfeet, brachial disorders, cognitive deficits, and pectoral muscle defects. Pathologic findings are variable and include brain stem nuclear aplasia, facial nerve aplasia, and facial muscle aplasia, consistent with a multifactorial etiology. (Adams et al., Principles of Neurology, 6th ed, p1020)
Poland Syndrome
A syndrome which is characterized by symbrachydactyly and aplasia of the sternal head of pectoralis major.
Audiometry, Pure-tone
Measurement of hearing based on the use of pure tones of various frequencies and intensities as auditory stimuli.
PubMed Articles
Several immune disorders are often associated with thymoma. The aim of this study was to analyze the correlation between clinicopathological features of Thai patients with thymoma and concomitant immu...
Ectopic Cervical Thymoma Accompanied by Good's Syndrome.
Ectopic cervical thymoma (ECT) is a rare tumor that is frequently misdiagnosed as a thyroid tumor or other malignancy. A 34-year-old male with a right palpable neck mass had been mistakenly diagnosed...
Myelodysplastic syndrome with erythroblastopenia.
Myelodysplastic syndrome with erythroid hypoplasia or erythroblastopenia has not yet been clearly defined, and in most patients it is mistaken for acquired pure red cell aplasia. Including one additio...
The thymus is a central lymphatic organ that is responsible for many immunological functions, including the production of mature, functional T cells and the induction of self-tolerance. Benign or mali...
Aquaporin-4 water channel expression by thymoma of patients with and without myasthenia gravis.
BACKGROUND: Neuromyelitis optica (NMO) is a serious idiopathic inflammatory demyelinating disorder characterized by acute transverse myelitis and optic neuritis. A significant proportion of NMO patien...
Clinical Trials
The purpose of this study is to investigate a possible relationship between antibodies to recombinant erythropoietin and the clinical course of Pure Red Cell Anemia (PRCA) in patients curr...
The purpose of this study is to record the number of patients with chronic renal disease who are receiving treatment with epoetin alfa or other recombinant erythropoietins who develop pure...
The purpose of this study is to record the number of patients with chronic renal disease who are receiving treatment with epoetin alfa or other recombinant erythropoietins who develop pure...
The purpose of this study is to collect and compare information from patients with chronic kidney disease who were treated with a recombinant erythropoietin marketed by the Johnson and Joh...
Rituximab to Treat Moderate Aplastic Anemia, Pure Red Cell Aplasia, or Diamond Blackfan Anemia
This study will test whether the immune-suppressing drug rituximab can increase blood counts and reduce the need for transfusions in patients with moderate aplastic anemia, pure red cell a...
