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Cathepsin L and B as Potential Markers for Liver Fibrosis: Insights From Patients and Experimental Models.

08:00 EDT 15th June 2017 | BioPortfolio

Summary of "Cathepsin L and B as Potential Markers for Liver Fibrosis: Insights From Patients and Experimental Models."

Cathepsin L (CTSL) and B (CTSB) have a crucial role in extracellular matrix (ECM) degradation and tissue remodeling, which is a prominent feature of fibrogenesis. The aim of this study was to determine the role and clinical significance of these cathepsins in liver fibrosis.

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This article was published in the following journal.

Name: Clinical and translational gastroenterology
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Pages: e99

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Medical and Biotech [MESH] Definitions

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An aspartic endopeptidase that is similar in structure to CATHEPSIN D. It is found primarily in the cells of the immune system where it may play a role in processing of CELL SURFACE ANTIGENS.

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