Nocardia transvalensis pulmonary infection in an immunocompetent patient with radiographic findings consistent with nontuberculous mycobacterial infections.
Summary of "Nocardia transvalensis pulmonary infection in an immunocompetent patient with radiographic findings consistent with nontuberculous mycobacterial infections."
A chest roentgenogram of a 75-year-old immunocompetent woman showed disseminated micronodular densities in bilateral lung fields. Subsequent high-resolution computed tomography (CT) confirmed centrilobular micronodular densities associated with bronchial wall thickening and bronchiectatic changes. CT imaging also revealed volume loss with bronchiectatic changes in both the right middle lobe and the left lingular segment. Cytology specimens were then obtained through bronchial brushing and washes. Smears from right B2 and B4 revealed filamentous gram-positive, branched bacteria embedded among many neutrophils. Nocardia transvalensis was cultured from the bronchial wash, and no mycobacteria were identified. To our knowledge, this is the first report of a Nocardia transvalensis pulmonary infection in an immunocompetent patient, and also the first detailed description of a Nocardia transvalensis pulmonary infection in Japan. Moreover, the radiographic and CT findings in this patient were quite similar to those seen in patients with nontuberculous mycobacterial pulmonary infections, a pattern not previously reported in patients with Nocardia pulmonary infections.
Division of Respiratory Medicine, National Hospital Organization Omuta National Hospital, 1044-1 Oaza, Tachibana, Omuta, 837-0911, Japan, firstname.lastname@example.org.
This article was published in the following journal.
Name: Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy
- PubMed Source: http://www.ncbi.nlm.nih.gov/pubmed/21567235
- DOI: http://dx.doi.org/10.1007/s10156-011-0243-0
Medical and Biotech [MESH] Definitions
Pulmonary or extrapulmonary infection caused by MYCOBACTERIUM TUBERCULOSIS or nontuberculous mycobacteria in a patient with silicosis.
A species of bacterium of the family NOCARDIACEAE, producing pulmonary infections in man.
Infections with bacteria of the genus NOCARDIA.
The segregation of patients with communicable or other diseases for a specified time. Isolation may be strict, in which movement and social contacts are limited; modified, where an effort to control specified aspects of care is made in order to prevent cross infection; or reverse, where the patient is secluded in a controlled or germ-free environment in order to protect him or her from cross infection.
Any infection which a patient contracts in a health-care institution.
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