MicroRNA regulated defense responses in Triticum aestivum L. during Puccinia graminis f.sp. tritici infection.
Summary of "MicroRNA regulated defense responses in Triticum aestivum L. during Puccinia graminis f.sp. tritici infection."
Plants have evolved diverse mechanism to recognize pathogen attack and triggers defense responses. These defense responses alter host cellular function regulated by endogenous, small, non-coding miRNAs. To understand the mechanism of miRNAs regulated cellular functions during stem rust infection in wheat, we investigated eight different miRNAs viz. miR159, miR164, miR167, miR171, miR444, miR408, miR1129 and miR1138, involved in three different independent cellular defense response to infection. The investigation reveals that at the initiation of disease, accumulation of miRNAs might be playing a key role in hypersensitive response (HR) from host, which diminishes at the maturation stage. This suggests a possible host-fungal synergistic relation leading to susceptibility. Differential expression of these miRNAs in presence and absence of R gene provides a probable explanation of miRNA regulated R gene mediated independent pathways.
Affiliation
Division of Biochemistry, Indian Agricultural Research Institute, New Delhi, 110012, India.
Journal Details
This article was published in the following journal.
Name: Molecular biology reports
ISSN: 1573-4978
Pages:
Links
- PubMed Source: http://www.ncbi.nlm.nih.gov/pubmed/21633895
- DOI: http://dx.doi.org/10.1007/s11033-011-0803-5
Medical and Biotech [MESH] Definitions
Receptors, Pattern Recognition
A large family of cell surface receptors that bind conserved molecular structures present in pathogens. They play important roles in host defense by mediating cellular responses to pathogens.
Repression-sensitization
Defense mechanisms involving approach and avoidance responses to threatening stimuli. The sensitizing process involves intellectualization in approaching or controlling the stimulus whereas repression involves unconscious denial in avoiding the stimulus.
Extracellular Signal-regulated Map Kinases
A mitogen-activated protein kinase subfamily that is widely expressed and plays a role in regulation of MEIOSIS; MITOSIS; and post mitotic functions in differentiated cells. The extracellular signal regulated MAP kinases are regulated by a broad variety of CELL SURFACE RECEPTORS and can be activated by certain CARCINOGENS.
Secale Cereale
A hardy grain crop, rye, grown in northern climates. It is the most frequent host to ergot (CLAVICEPS), the toxic fungus. Its hybrid with TRITICUM is TRITICALE, another grain.
P38 Mitogen-activated Protein Kinases
A mitogen-activated protein kinase subfamily that regulates a variety of cellular processes including CELL GROWTH PROCESSES; CELL DIFFERENTIATION; APOPTOSIS; and cellular responses to INFLAMMATION. The P38 MAP kinases are regulated by CYTOKINE RECEPTORS and can be activated in response to bacterial pathogens.
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