Immune complex reaction after successful treatment of meningococcal disease: an excellent response to IVIG.
Summary of "Immune complex reaction after successful treatment of meningococcal disease: an excellent response to IVIG."
The convalescence phase of severe meningococcal sepsis is complicated by immune complex reactions with arthritis being the commonest. No standard guidelines exist for management of such complications, but non-steroidal anti-inflammatory drugs and steroids have been used with varying success. We report excellent response to intravenous immunoglobulin in a child with immune complex reaction following meningococcal sepsis.
Affiliation
Department of Pediatric Disciplines, North Eastern Indira Gandhi Regional Institute of Health and Medical Sciences, Room no. 218, PO: Mawdiangdiang, Shillong, Meghalaya, 793018, India, rashnadass@rediffmail.com.
Journal Details
This article was published in the following journal.
Name: Rheumatology international
ISSN: 1437-160X
Pages:
Links
- PubMed Source: http://www.ncbi.nlm.nih.gov/pubmed/20658236
- DOI: http://dx.doi.org/10.1007/s00296-010-1555-6
Medical and Biotech [MESH] Definitions
Disease-free Survival
Period after successful treatment in which there is no appearance of the symptoms or effects of the disease.
Immune Complex Diseases
Group of diseases mediated by the deposition of large soluble complexes of antigen and antibody with resultant damage to tissue. Besides SERUM SICKNESS and the ARTHUS REACTION, evidence supports a pathogenic role for immune complexes in many other IMMUNE SYSTEM DISEASES including GLOMERULONEPHRITIS, systemic lupus erythematosus (LUPUS ERYTHEMATOSUS, SYSTEMIC) and POLYARTERITIS NODOSA.
Antigens
Substances that are recognized by the immune system and induce an immune reaction.
Bovine Respiratory Disease Complex
A multifactorial disease of CATTLE resulting from complex interactions between environmental factors, host factors, and pathogens. The environmental factors act as stressors adversely affecting the IMMUNE SYSTEM and other host defenses and enhancing transmission of infecting agents.
Vaccines, Dna
Recombinant DNA vectors encoding antigens administered for the prevention or treatment of disease. The host cells take up the DNA, express the antigen, and present it to the immune system in a manner similar to that which would occur during natural infection. This induces humoral and cellular immune responses against the encoded antigens. The vector is called naked DNA because there is no need for complex formulations or delivery agents; the plasmid is injected in saline or other buffers.
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