Recurrent adenoid cystic carcinoma in the liver: a repeated laparoscopic surgical approach.

22:01 EDT 1st September 2014 | BioPortfolio

Summary of "Recurrent adenoid cystic carcinoma in the liver: a repeated laparoscopic surgical approach."

Adenoid cystic carcinoma (ACC) is characterized by a particularly aggressive behavior even many years after resection of primary tumor. The evolution of metastasis dramatically affects the final outcome but resection should always be evaluated. Herein is described a case of aggressive ACC of the parotid gland in a 30-year-old female. She developed local recurrence and lung metastases; then, she also developed two liver metastasis 112 and 132 months after the resection of the primitive cancer of the parotid gland. Both lesions were successfully managed by a laparoscopic approach. Intra-abdominal adhesions after the first surgery were mild, allowing an easier access for the second laparoscopic liver resection. At 1 year follow-up, the patient is liver disease free with a stable lung disease. To our knowledge, this is the first report of a double laparoscopic liver resection for parotid gland's ACC metachronous metastases. Patients with resected ACC need a strict and lifelong follow-up after the resection of the primitive cancer. Also for ACC, a laparoscopic approach to liver metastasis should always be considered as a viable alternative to open surgery. In our experience of over 90 cases, laparoscopic surgery causes less adhesions, allowing an easier approach for repeated resections.

Affiliation

Hepatobiliary Surgery and Liver Transplant Unit, "A. Cardarelli" Hospital, Via A. Cardarelli, 9, 80131, Naples, Italy, scuderi.enzo@gmail.com.

Journal Details

This article was published in the following journal.

Name: Updates in surgery
ISSN: 2038-131X
Pages:

Links

PubMed Articles [17673 Associated PubMed Articles listed on BioPortfolio]

A case of hepatic resection of liver metastasis 8 years after resection of an adenoid cystic carcinoma of the parotid gland.

We performed surgical resection for a case of hepatic metastasis of an adenoid cystic carcinoma of the parotid gland. A 53-year-old woman underwent parotidectomy for primary adenoid cystic carcinoma i...

Adenoid Cystic Carcinoma of the Buccal Mucosa: A Case Report with Review of Literature.

Minor salivary gland neoplasms of the buccal mucosa are relatively uncommon. Adenoid cystic carcinoma (ACC), a well-defined entity, occurs most of the times in the parotid, submandibular glands and pa...

Adenoid cystic carcinoma of the breast: A case report and literature review.

Adenoid cystic carcinoma (ACC) is a rare malignant tumor of the breast that occurs in

Chemoradiotherapy with irinotecan (CPT-11) for adenoid cystic carcinoma of Bartholin's gland: A case report and review of the literature.

► Adenoid cystic carcinoma of Bartholin's gland is extremely rare, and only 80 cases have been reported in the international literature. ► We have presented a case in which a favorable outcome was...

Male breast adenoid cystic carcinoma.

Adenoid cystic carcinoma (ACC) of the breast is a rare condition, and cases in male patients are even less common.

Clinical Trials [5789 Associated Clinical Trials listed on BioPortfolio]

Study of RAD001 in Adenoid Cystic Carcinoma

- Although mTOR is clearly an attractive therapeutic target in tumor, no clinical study on mTOR inhibition by RAD001 has been systematically conducted in adenoid cystic carcinom...

A Study of Sunitinib in Recurrent and/or Metastatic Adenoid Cystic Carcinoma of the Salivary Glands

This is a phase II study to evaluate the effectiveness of study drug sunitinib malate in patients with recurrent and/or metastatic adenoid cystic carcinomas of the salivary gland. There cu...

Nelfinavir in Recurrent Adenoid Cystic Cancer of the Head and Neck

The purpose of this study is to evaluate the FDA-approved drug nelfinavir (NFV) as an oncologic agent for adenoid cystic cancers of the head and neck. Specifically, subjects will be asked...

Phase II Trial of Doxorubicin and Bortezomib in Patients With Incurable Adenoid Cystic Carcinoma of the Head and Neck

This is a Phase II trial non-randomized study to evaluate the objective response rate and stable disease rate (primary endpoints), progression-free survival, overall survival and toxicitie...

Study of Imatinib (Glivec) in Patients With Adenoid Cystic Carcinoma of the Head and Neck

This is a Phase II study of imatinib (Glivec) administered as a daily oral treatment in patients with recurrent/metastatic adenoid cystic carcinoma of the head and neck overexpressing KIT.

Medical and Biotech [MESH] Definitions

Carcinoma characterized by bands or cylinders of hyalinized or mucinous stroma separating or surrounded by nests or cords of small epithelial cells. When the cylinders occur within masses of epithelial cells, they give the tissue a perforated, sievelike, or cribriform appearance. Such tumors occur in the mammary glands, the mucous glands of the upper and lower respiratory tract, and the salivary glands. They are malignant but slow-growing, and tend to spread locally via the nerves. (Dorland, 27th ed)

A cystic form of sweat gland adenoma (ADENOMA, SWEAT GLAND). It is produced by the cystic proliferation of apocrine secretory glands. It is not uncommon, occurring in adult life in no particular age group, with males and females equally affected. The commonest site is around the eye, particularly lateral to the outer canthus. It is cured by surgical removal. (Stedman, 25th ed; Rook et al., Textbook of Dermatology, 4th ed, p2410)

Procedures that avoid use of open invasive surgery in favor of closed or local surgery. These generally involve use of laparoscopic devices and remote-control manipulation of instruments with indirect observation of the surgical field through an endoscope or similar device. With the reduced trauma associated with minimally invasive surgery, long hospital stays may be reduced with increased rates of short stay or day surgery.

Cystic mass containing lymph from diseased lymphatic channels or following surgical trauma or other injury.

Surgical procedures conducted with the aid of computers. This is most frequently used in orthopedic and laparoscopic surgery for implant placement and instrument guidance. Image-guided surgery interactively combines prior CT scans or MRI images with real-time video.

Search BioPortfolio:
Advertisement

Relevant Topic

Pulmonary
Latest News Clinical Trials Research Drugs Reports Corporate
Pulmonary relating to or associated with the lungs eg Asthma, chronic bronchitis, emphysema, COPD, Cystic Fibrosis, Influenza,  Lung Cancer, Pneumonia, Pulmonary Arterial Hypertension, Sleep Disorders etc Follow and track Lung Cancer News ...

Advertisement