Molecular markers in medicinal plant biotechnology: past and present.
Summary of "Molecular markers in medicinal plant biotechnology: past and present."
Plant based medicines have gained popularity worldwide due to their almost negligible side effects. In India, the three traditional medicinal systems, namely homeopathy, Ayurveda and Siddha rely heavily on plants for medicinal formulations. To prevent the indiscriminate collection of these valuable medicinal plants and for their proper authentication and conservation, it is imperative to go for sustained efforts towards proper germplasm cataloguing and devising conservation strategies. For this purpose, molecular markers have a significant role, as they provide information ranging from diversity at nucleotide level (single nucleotide polymorphisms) to gene and allele frequencies (genotype information), the extent and distribution of genetic diversity, and population structure. Over the past twenty years, the molecular marker field has completely transformed the meaning of conservation genetics which has emerged from a theory-based field of population biology to a full-fledged pragmatic discipline. In this review, we have explored the transition and transformation of molecular marker technologies throughout these years.
Affiliation
Department of Biotechnology, Faculty of Science, Jamia Hamdard, New Delhi, India.
Journal Details
This article was published in the following journal.
Name: Critical reviews in biotechnology
ISSN: 1549-7801
Pages:
Links
- PubMed Source: http://www.ncbi.nlm.nih.gov/pubmed/21649550
- DOI: http://dx.doi.org/10.3109/07388551.2011.551872
Medical and Biotech [MESH] Definitions
Molecular Epidemiology
The application of molecular biology to the answering of epidemiological questions. The examination of patterns of changes in DNA to implicate particular carcinogens and the use of molecular markers to predict which individuals are at highest risk for a disease are common examples.
Cells, Immobilized
Microbial, plant, or animal cells which are immobilized by attachment to solid structures, usually a column matrix. A common use of immobilized cells is in biotechnology for the bioconversion of a substrate to a particular product. (From Singleton & Sainsbury, Dictionary of Microbiology and Molecular Biology, 2d ed)
Salvia Miltiorrhiza
A plant species which is known as an Oriental traditional medicinal plant.
Rosmarinus
A plant genus of the LAMIACEAE family. It is known as a spice and medicinal plant.
Markov Chains
A stochastic process such that the conditional probability distribution for a state at any future instant, given the present state, is unaffected by any additional knowledge of the past history of the system.
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