Malignant versus benign mediastinal lesions: quantitative assessment with diffusion weighted MR imaging.

16:23 EDT 29th August 2014 | BioPortfolio

Summary of "Malignant versus benign mediastinal lesions: quantitative assessment with diffusion weighted MR imaging."


OBJECTIVES:
We aimed to evaluate the performance of diffusion-weighted magnetic resonance imaging in differentiating malignant from benign mediastinal lesions.
METHODS:
Fifty-three mediastinal lesions were examined with T1- and T2-weighted (W) conventional images. Then, two diffusion-weighted images were obtained with b = 0 and 1000 s/mm² values and apparent diffusion coefficients (ADC) were calculated. The statistical significance of differences between measurements was tested using the Student-t test.
RESULTS:
The mean ADC of malignant lesions was significantly lower than that of the benign masses (p < 0.001). The cut-off value of ≤ 1.39 × 10(-3) mm²/s indicated a malignant lesion with a sensitivity of 95% and specificity of 87%.
CONCLUSION:
Diffusion-weighted imaging may be helpful in differentiating benign from malignant mediastinal masses.

Affiliation

Department of Radiology, School of Medicine, University of Kocaeli, Kocaeli Uni. Tip Fak Radyoloji AD, 41380, Umuttepe Kocaeli, Turkey, svtgumustas@hotmail.com.

Journal Details

This article was published in the following journal.

Name: European radiology
ISSN: 1432-1084
Pages:

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