Advertisement

Topics

Malignant versus benign mediastinal lesions: quantitative assessment with diffusion weighted MR imaging.

Summary of "Malignant versus benign mediastinal lesions: quantitative assessment with diffusion weighted MR imaging."


OBJECTIVES:
We aimed to evaluate the performance of diffusion-weighted magnetic resonance imaging in differentiating malignant from benign mediastinal lesions.
METHODS:
Fifty-three mediastinal lesions were examined with T1- and T2-weighted (W) conventional images. Then, two diffusion-weighted images were obtained with b = 0 and 1000 s/mm² values and apparent diffusion coefficients (ADC) were calculated. The statistical significance of differences between measurements was tested using the Student-t test.
RESULTS:
The mean ADC of malignant lesions was significantly lower than that of the benign masses (p < 0.001). The cut-off value of ≤ 1.39 × 10(-3) mm²/s indicated a malignant lesion with a sensitivity of 95% and specificity of 87%.
CONCLUSION:
Diffusion-weighted imaging may be helpful in differentiating benign from malignant mediastinal masses.

Affiliation

Department of Radiology, School of Medicine, University of Kocaeli, Kocaeli Uni. Tip Fak Radyoloji AD, 41380, Umuttepe Kocaeli, Turkey, svtgumustas@hotmail.com.

Journal Details

This article was published in the following journal.

Name: European radiology
ISSN: 1432-1084
Pages:

Links

DeepDyve research library

PubMed Articles [18564 Associated PubMed Articles listed on BioPortfolio]

Quantitative differentiation of benign and malignant mammographic circumscribed masses using intensity histograms.

To investigate the usefulness of density gradient of mammographic masses for differentiating benign from malignant lesions, particularly circumscribed masses, which are difficult to diagnose by shape.

A novel two-dimensional quantitative shear wave elastography for differentiating malignant from benign breast lesions.

The purpose of this study was to evaluate the diagnostic performance of a novel quantitative shear wave elastography (SWE) of virtual touch tissue imaging quantification (VTIQ) in diagnosis of breast ...

MicroRNAs as novel biomarkers for the differentiation of malignant versus benign thyroid lesions: a meta-analysis.

The aim of this meta-analysis was to systematically evaluate the diagnostic accuracy of microRNAs (miRNAs) in distinguishing malignant thyroid lesions from benign ones and to determine the potential o...

Retrospective Assessment of Histogram-Based Diffusion Metrics for Differentiating Benign and Malignant Endometrial Lesions.

Our study aimed to retrospectively evaluate the utility of volumetric histogram-based diffusion metrics in differentiating benign from malignant endometrial abnormalities.

Optical coherence tomography accurately identifies patients with penile (pre) malignant lesions: A single center prospective study.

Currently, (multiple) biopsies are taken to obtain histopathological diagnosis of suspicious lesions of the penile skin. Optical coherence tomography (OCT) provides noninvasive in vivo images from whi...

Clinical Trials [5303 Associated Clinical Trials listed on BioPortfolio]

Use of PET Imaging to Distinguish Malignant From Benign IPMN

Intraductal papillary mucinous neoplasm (IPMN) is a cystic pancreatic lesion that is a precursor to invasive pancreatic cancer. Differentiating whether an IPMN lesion is benign or malignan...

Contrast-Enhanced Ultrasound Ability in the Characterization of Ovarian Masses

This study intends to assess the ability of contrast-enhanced ultrasound in the detection of benign and malignant ovarian masses compared to unenhanced ultrasound. By using an intravascul...

Endobronchial Ultrasound Guided Transbronchial Lung Biopsy With or Without Guide Sheath in Lung Tumors and the Analysis of Echoic Patterns of Lung Tumors and Mediastinal Lymph Nodes, and the Association Between Diagnostic Yield of Transbronchial Lung Biop

1. Endobronchial ultrasonography (EBUS) is useful in localizing peripheral lung lesions. The EBUS, further combined with the guide sheath (GS) technique, has been reported to inc...

Quantitative Real-time Ultrasound Elastography for Characterisation of Liver Tumors

Shear Wave Elastography (SWE™) is a quantitative elastography method for measuring tissue stiffness. The difference in stiffness between benign and malignant tumors has been demonstrate...

Anterior Mediastinum Teratoma: A Case Report

The investigators report a case of a 39-year-old man who presented an anterior mediastinal cystic mature teratoma. Those kind of tumor contain elements derived from more than one of the th...

Medical and Biotech [MESH] Definitions

A tumor composed of spindle cells with a rich vascular network, which apparently arises from pericytes, cells of smooth muscle origin that lie around small vessels. Benign and malignant hemangiopericytomas exist, and the rarity of these lesions has led to considerable confusion in distinguishing between benign and malignant variants. (From Dorland, 27th ed; DeVita Jr et al., Cancer: Principles & Practice of Oncology, 3d ed, p1364)

A genus of DNA viruses in the family PAPILLOMAVIRIDAE. They preferentially infect the anogenital and ORAL MUCOSA in humans and primates, causing both malignant and benign neoplasms. Cutaneous lesions are also seen.

Presence of air in the mediastinal tissues due to leakage of air from the tracheobronchial tree, usually as a result of trauma.

A group of disorders having a benign course but exhibiting clinical and histological features suggestive of malignant lymphoma. Pseudolymphoma is characterized by a benign infiltration of lymphoid cells or histiocytes which microscopically resembles a malignant lymphoma. (From Dorland, 28th ed & Stedman, 26th ed)

The qualitative or quantitative estimation of the likelihood of adverse effects that may result from exposure to specified health hazards or from the absence of beneficial influences. (Last, Dictionary of Epidemiology, 1988)

Quick Search
Advertisement
 


DeepDyve research library

Relevant Topic

Radiology
Radiology is the branch of medicine that studies imaging of the body; X-ray (basic, angiography, barium swallows), ultrasound, MRI, CT and PET. These imaging techniques can be used to diagnose, but also to treat a range of conditions, by allowing visuali...


Searches Linking to this Article