Application of thin metal film elements in bioanalysis.

06:00 EDT 9th July 2011 | BioPortfolio

Summary of "Application of thin metal film elements in bioanalysis."

Advanced metal deposition and microfabrication techniques enable preparation of metal surfaces with high precision and excellent control over their size and shape with subnanometer resolution. Thin metal films of different types and functions can be found in many analytical instruments. Surfaces with high optical quality serve as mirrors, beam splitters, antireflective coatings etc. Smooth metal coating is crucial in electron microscopy. Unique properties of the thin metal films are widely used in optical systems, as tools for sample manipulation but also for chemical sensing and detection. While some of the applications are widespread and belong to the basic curriculum in analytical chemistry, the newer or less common uses of thin metal films are well known only to the experts in the field. The purpose of this critical review is to highlight the role of thin metal films in bioanalysis and summarize some of their main applications in current bioanalytical instrumentation.


Institute of Analytical Chemistry ASCR, v.v.i., Brno, Czech Republic.

Journal Details

This article was published in the following journal.

Name: Journal of separation science
ISSN: 1615-9314


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