Anaerobicizing into pluripotency.
Summary of "Anaerobicizing into pluripotency."
Reprogramming involves multiple layers of molecular regulation, yet it remains relatively unknown how the cell's metabolism is changing and/or contributing to this process. In this issue of Cell Metabolism, Folmes et al. (2011) demonstrate that reprogramming induces a bioenergetic transition from an oxidative to a glycolytic state, and provide evidence to suggest that these changes may precede pluripotency.
Affiliation
Gene Expression Laboratory, The Salk Institute for Biological Studies, 10010 North Torrey Pines, La Jolla, CA 92037, USA.
Journal Details
This article was published in the following journal.
Name: Cell metabolism
ISSN: 1932-7420
Pages: 143-4
Links
- PubMed Source: http://www.ncbi.nlm.nih.gov/pubmed/21803281
- DOI: http://dx.doi.org/10.1016/j.cmet.2011.07.003
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