Are Modic changes prognostic for recovery in a cohort of patients with non-specific low back pain?
Summary of "Are Modic changes prognostic for recovery in a cohort of patients with non-specific low back pain?"
BACKGROUND:
There is evidence for an association between Modic type 1 and pain in patients with low back pain (LBP), but little knowledge about its effect on clinical outcomes.
PURPOSE:
(1) To assess the prevalence of Modic changes, (2) to determine if Modic changes influence the clinical course of LBP, and (3) to identify prognostic factors for recovery. STUDY DESIGN/
SETTING:
Prospective clinical cohort study, with a 1-year follow-up. The treatment consisted of brief intervention and instruction in stretching. PATIENT'S
SAMPLE:
Two hundred and sixty-nine patients with chronic low back pain. OUTCOME
MEASURES:
Socio-demographic variables, education, profession, self-reported measures, degenerative changes on MRI.
METHODS:
Linear growth model and Cox regression analysis.
RESULTS:
Five percent had a normal MRI, 14 and 50% had Modic 1 and Modic 2 changes. Modic changes were not significant covariates for the clinical course of pain, function or fear avoidance beliefs. Education was a strong prognostic factor for recovery.
CONCLUSIONS:
Modic changes did not influence the clinical course of back pain and were not prognostic factors for recovery. Education was strongly associated with recovery.
Affiliation
Department of Physical Medicine and Rehabilitation, Oslo University Hospital, 0407, Oslo, Norway, Anne.Keller@medisin.uio.no.
Journal Details
This article was published in the following journal.
Name: European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the Euro
ISSN: 1432-0932
Pages:
Links
- PubMed Source: http://www.ncbi.nlm.nih.gov/pubmed/21837412
- DOI: http://dx.doi.org/10.1007/s00586-011-1964-6
Medical and Biotech [MESH] Definitions
Cohort Effect
Variation in health status arising from different causal factors to which each birth cohort in a population is exposed as environment and society change.
Comparative Effectiveness Research
Conduct and synthesis of systematic research comparing interventions and strategies to prevent, diagnose, treat, and monitor health conditions. The purpose of this research is to inform patients, providers, and decision-makers, responding to their expressed needs, about which interventions are most effective for which patients under specific circumstances. (hhs.gov/recovery/programs/cer/draftdefinition.html accessed 6/12/2009)
Sentinel Surveillance
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Nomograms
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