FUNDUS AUTOFLUORESCENCE AND OPTICAL COHERENCE TOMOGRAPHIC FINDINGS IN ACUTE ZONAL OCCULT OUTER RETINOPATHY.
Summary of "FUNDUS AUTOFLUORESCENCE AND OPTICAL COHERENCE TOMOGRAPHIC FINDINGS IN ACUTE ZONAL OCCULT OUTER RETINOPATHY."
PURPOSE:
: The purpose of this study was to investigate the fundus autofluorescence and optical coherence tomography findings in eyes with acute zonal occult outer retinopathy (AZOOR).
METHODS:
: A retrospective observational case series of the fundus autofluorescence and spectral domain optical coherence tomography in a series of patients with AZOOR.
RESULTS:
: There were 19 eyes of 11 patients (10 women), who had a mean age of 49.1 +/- 13.9 years. Fundus autofluorescence abnormalities were seen in 17 of the 19 eyes, were more common in the peripapillary area, and were smaller in extent than the optical coherence tomography abnormalities. Nine eyes showed progression of hypoautofluorescence area during the mean follow-up of 69.7 months. The mean thickness of the photoreceptor layer at fovea was 177 mum in eyes with AZOOR, which was significantly thinner than controls (193 mum, P = 0.049). Abnormal retinal laminations were found in 12 eyes and were located over areas of loss of the photoreceptors. The subfoveal choroidal thickness was 243 mum, which is normal.
CONCLUSION:
: Fundus autofluorescence abnormalities in AZOOR showed distinct patterns of retinal pigment epithelial involvement, which may be progressive. Thinning of photoreceptor cell layer with loss of the outer segments and abnormal inner retinal lamination in the context of a normal choroid are commonly found in AZOOR.
Affiliation
From the *LuEsther T. Mertz Retinal Research Center, Manhattan Eye, Ear & Throat Hospital, New York, New York; and daggerVitreous-Retina-Macula Consultants of New York, New York.
Journal Details
This article was published in the following journal.
Name: Retina (Philadelphia, Pa.)
ISSN: 1539-2864
Pages:
Links
- PubMed Source: http://www.ncbi.nlm.nih.gov/pubmed/20661173
- DOI: http://dx.doi.org/10.1097/IAE.0b013e3181e097f0
Medical and Biotech [MESH] Definitions
Tomography, Optical Coherence
An imaging method using LASERS that is used for mapping subsurface structure. When a reflective site in the sample is at the same optical path length (coherence) as the reference mirror, the detector observes interference fringes.
Pancreatitis
INFLAMMATION of the PANCREAS. Pancreatitis is classified as acute unless there are computed tomographic or endoscopic retrograde cholangiopancreatographic findings of CHRONIC PANCREATITIS (International Symposium on Acute Pancreatitis, Atlanta, 1992). The two most common forms of acute pancreatitis are ALCOHOLIC PANCREATITIS and gallstone pancreatitis.
Uterus
The hollow thick-walled muscular organ in the female PELVIS. It consists of the fundus (the body) which is the site of EMBRYO IMPLANTATION and FETAL DEVELOPMENT. Beyond the isthmus at the perineal end of fundus, is CERVIX UTERI (the neck) opening into VAGINA. Beyond the isthmi at the upper abdominal end of fundus, are the FALLOPIAN TUBES.
Colonography, Computed Tomographic
A non-invasive imaging method that uses computed tomographic data combined with specialized imaging software to examine the colon.
Optical Devices
Products or parts of products used to detect, manipulate, or analyze light, such as LENSES, refractors, mirrors, filters, prisms, and OPTICAL FIBERS.
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