The Diversity of Wound Presentation Associated With Freon Contact Frostbite Injury.
Summary of "The Diversity of Wound Presentation Associated With Freon Contact Frostbite Injury."
The authors report two cases of patients presenting with chemical frostbite-like injuries to the hands and wrists after contact exposure to Freon liquid. Although the history and initial physical presentations were quite similar, the severity of these injuries varied widely from superficial bullae to deep tissue injuries, requiring skin grafting and amputation of several digits. Freon is a widely used coolant in refrigerators, air conditioners, freezers, and water coolers, with a boiling point of -41 degrees C. Although several cases of Freon-induced inhalational injury have been reported, few case reports of Freon-associated contact skin injury exist in the literature. The authors detail the broad diversity of injuries resulting from Freon contact as well as the first report of severe Freon injury necessitating skin grafting and amputation of multiple digits.
From the *Department of Medicine, Duke University Medical Center, Durham, North Carolina; and daggerDepartment of Surgery, The Ohio State University Center for Burn Care, The Ohio State University Medical Center, Columbus, Ohio.
This article was published in the following journal.
Name: Journal of burn care & research : official publication of the American Burn Association
- PubMed Source: http://www.ncbi.nlm.nih.gov/pubmed/20661149
- DOI: http://dx.doi.org/10.1097/BCR.0b013e3181eed452
Significance: Rare bacterial taxa (taxa of low relative frequency) are numerous and ubiquitous in virtually any sample-including wound samples. In addition, even the high-frequency genera and species ...
Wound therapy improves every year by developing new wound treatment options or by advancing already existing wound materials, for example, adding self-releasing analgesic drugs or growth factors to wo...
Obstructive Airway Disease CasesSESSION TYPE: Affiliate Case Report SlidePRESENTED ON: Sunday, October 26, 2014 at 03:15 PM - 04:15 PMINTRODUCTION: Freon 12B2 is widely used as a refrigerant, solvent ...
Effective wound management is dependent, in part, on identification and correction of causative factors. Trunk wounds can be caused by pressure, shear, moisture, friction, or some combination of these...
Inhalation of volatile substances is a cheap and accessible way for individuals, most commonly teenagers, to ingest mind-altering substances. The adverse effects of using inhalants, including cardiac ...
The purpose of this study is to evaluate the effectiveness of MIST Therapy in combination with standard of care (SOC) compared to SOC alone on reducing the bacteria in your wound and prepa...
The UltraHeal Study is a randomized controlled trial to compare healing response of low frequency contact ultrasonic-assisted debridement in addition to best practice wound care to best pr...
The purpose of this study is to evaluate the effect of ProKera on corneal wound healing after photorefractive keratectomy (PRK) in terms of re-epithelialization, pain, adverse effects, vis...
- After determining if subjects meet the criteria to be included in the study, the wound will be debrided (cleansed of any dead tissue or infection). - Subjects will then be rand...
To assess, in donor-recipient clusters, current models of HIV-1 genetic evolution and pathogenesis, based on the sequence diversity displayed by this lentivirus.
Medical and Biotech [MESH] Definitions
The application of a vacuum across the surface of a wound through a foam dressing cut to fit the wound. This removes wound exudates, reduces build-up of inflammatory mediators, and increases the flow of nutrients to the wound thus promoting healing.
The phenomenon of immense variability characteristic of ANTIBODIES. It enables the IMMUNE SYSTEM to react specifically against the essentially unlimited kinds of ANTIGENS it encounters. Antibody diversity is accounted for by three main theories: (1) the Germ Line Theory, which holds that each antibody-producing cell has genes coding for all possible antibody specificities, but expresses only the one stimulated by antigen; (2) the Somatic Mutation Theory, which holds that antibody-producing cells contain only a few genes, which produce antibody diversity by mutation; and (3) the Gene Rearrangement Theory, which holds that antibody diversity is generated by the rearrangement of IMMUNOGLOBULIN VARIABLE REGION gene segments during the differentiation of the ANTIBODY-PRODUCING CELLS.
Class I-restricted activation of CD8-POSITIVE LYMPHOCYTES resulting from ANTIGEN PRESENTATION of exogenous ANTIGENS (cross-presentation). This is in contrast to normal activation of these lymphocytes (direct-priming) which results from presentation of endogenous antigens.
Damage to tissues as the result of low environmental temperatures.
Removal of degenerated and necrotic epithelium and underlying connective tissue of a periodontal pocket in an effort to convert a chronic ulcerated wound to an acute surgical wound, thereby insuring wound healing and attachment or epithelial adhesion, and shrinkage of the marginal gingiva. The term is sometimes used in connection with smoothing of a root surface or ROOT PLANING. (Jablonski; Illustrated Dictionary of Dentistry, 1982)