Medication overuse as a cause of chronic headache in shunted hydrocephalus patients.

06:00 EDT 28th July 2010 | BioPortfolio

Summary of "Medication overuse as a cause of chronic headache in shunted hydrocephalus patients."

Purpose To highlight the group of hydrocephalus patients known to have a long history of shunt revisions and refractory chronic headache. When a shunt in perfect working order has no effect on headache, other causes of headache should be investigated. In this paper, patients with medication overuse headache are indentified and the positive effect of medication withdrawal are described. Materials and method Patients with hydrocephalus and shunt referred from the neurosurgical department to the Danish Headache Centre were identified. In all cases, over- and underdrainage was ruled out prior to referral. Six patients with medication overuse headache were documented and their charts were reviewed retrospectively with specific attention to: shunt revisions, inpatient and outpatient contacts, headache data and medication use before and after withdrawal of analgesic medication overuse. Results A marked reduction in shunt revisions and inpatient contacts in five out of six patients was found and a reduction in outpatient contacts in four out of six patients. Furthermore, an improvement in headache intensity was found in three out of six patients and a reduction in duration was found in two out of six patients. Conclusion This study indicates that it is important to identify shunt patients with persistent chronic headache from causes other than shunt malfunction. By reducing their analgesic intake, it is possible to reduce headaches, the number of surgical interventions and hospital contacts. Hopefully this will raise awareness and lead to further research on the subject.


Danish Headache Centre, Department of Neurology, Glostrup Hospital, University of Copenhagen, Denmark.

Journal Details

This article was published in the following journal.

Name: Journal of neurology, neurosurgery, and psychiatry
ISSN: 1468-330X


PubMed Articles [31646 Associated PubMed Articles listed on BioPortfolio]

Medication-overuse headache affects 1 to 2 percent of the population. Any kind of painkiller, if taken regularly at least 10 days per month can cause medication-overuse headache, and therefore the pos...

Temporomandibular disorder is more prevalent among patients with primary headaches in a tertiary outpatient clinic.

Objective The aim of this study was to estimate the prevalence of signs and symptoms of temporomandibular disorders (TMD) in patients with primary headaches attended in a tertiary neurology ambulatory...

Risk Factors for and Management of Medication-Overuse Headache.

This review focuses on patients with migraine who frequently use acute medications.

Prevalence of normal head CT and positive CT findings in a large cohort of patients with chronic headaches.

This study was carried out to ascertain the frequency of normal head computed tomography (CT) scans and positive CT scan findings in patients having chronic headache as chief complaint. Head CT scans ...

Frovatriptan possibly causing acute myocardial infarction.

Globally migraine affects more than 10% of the adult population and it is treated with simple analgesics, combined with a triptan for a stronger treatment effect. Triptans cause arterial vasoconstrict...

Clinical Trials [5554 Associated Clinical Trials listed on BioPortfolio]

Frovatriptan as a Transitional Therapy in Medication Overuse Headache

This study will analyze the effectiveness of a medication called Frovatriptan, in the context of medication overuse headache (MOH). MOH is a headache that develops when pain-killers are t...

Short Intervention for Medication Overuse Headache (MOH) - Pilot

The purpose of the study is to evaluate whether training of GPs in the detection and treatment of medication overuse headache leads to improved care for these patients as compared to "busi...

Orbitofrontal Cortex (OFC) Influence on Addictive Medication Overuse Headache (MOH) Deriving From Migraine

Medication Overuse Headache (MOH) is an illness affecting about 1,5 % of the general population. It is characterized by chronic headache occurring for at least 15 days a month, by a use of...

Prednisolone in the Treatment of Withdrawal Headache in Probable Medication Overuse Headache

The purpose of this study is to determine whether prednisolone is more effective than placebo in the first six days after initiation of medication withdrawal therapy for a medication overu...

Detoxification and Treatment of Subjects With Medication Overuse Headache

The purpose of this study is to assess the benefits of almotriptan used as a transitional therapy and topiramate in subjects with medication overuse headaches (MOH.

Medical and Biotech [MESH] Definitions

Assistance in managing and monitoring drug therapy for patients receiving treatment for cancer or chronic conditions such as asthma and diabetes, consulting with patients and their families on the proper use of medication; conducting wellness and disease prevention programs to improve public health; overseeing medication use in a variety of settings.

An intermittent and self-limiting headache disorder in individuals with CEREBROSPINAL FLUID SHUNTS emplaced for the treatment of HYDROCEPHALUS. The symptoms of headache, vomiting, and cranial neuropathies are associated with intermittent obstruction of the shunt.

Overall systems, traditional or automated, to provide medication to patients in hospitals. Elements of the system are: handling the physician's order, transcription of the order by nurse and/or pharmacist, filling the medication order, transfer to the nursing unit, and administration to the patient.

Excessive accumulation of cerebrospinal fluid within the cranium which may be associated with dilation of cerebral ventricles, INTRACRANIAL HYPERTENSION; HEADACHE; lethargy; URINARY INCONTINENCE; and ATAXIA (and in infants macrocephaly). This condition may be caused by obstruction of cerebrospinal fluid pathways due to neurologic abnormalities, INTRACRANIAL HEMORRHAGES; CENTRAL NERVOUS SYSTEM INFECTIONS; BRAIN NEOPLASMS; CRANIOCEREBRAL TRAUMA; and other conditions. Impaired resorption of cerebrospinal fluid from the arachnoid villi results in a communicating form of hydrocephalus. Hydrocephalus ex-vacuo refers to ventricular dilation that occurs as a result of brain substance loss from CEREBRAL INFARCTION and other conditions.

Overall systems, traditional or automated, to provide medication to patients.


Relevant Topics

Pharmacy is the science and technique of preparing as well as dispensing drugs and medicines. It is a health profession that links health sciences with chemical sciences and aims to ensure the safe and effective use of pharmaceutical drugs. The scope of...

Neurology - Central Nervous System (CNS)
Alzheimer's Disease Anesthesia Anxiety Disorders Autism Bipolar Disorders Dementia Epilepsy Multiple Sclerosis (MS) Neurology Pain Parkinsons Sleep Disorders Neurology is the branch of medicine concer...

Searches Linking to this Article