Yeast mating: trying out new pickup lines.
Summary of "Yeast mating: trying out new pickup lines."
Mating of Ascomycete fungi involves chemically distinct pheromones; one partner makes a lipid-modified peptide, the other partner a simple peptide. A new study has now found that this inherent asymmetry may not be necessary.
Affiliation
Biotechnology Research Institute, National Research Council of Canada, Montreal, Quebec, Canada.
Journal Details
This article was published in the following journal.
Name: Current biology : CB
ISSN: 1879-0445
Pages: R626-8
Links
- PubMed Source: http://www.ncbi.nlm.nih.gov/pubmed/21855002
- DOI: http://dx.doi.org/10.1016/j.cub.2011.06.060
Medical and Biotech [MESH] Definitions
Genes, Mating Type, Fungal
Fungal genes that mostly encode TRANSCRIPTION FACTORS. In some FUNGI they also encode PHEROMONES and PHEROMONE RECEPTORS. The transcription factors control expression of specific proteins that give a cell its mating identity. Opposite mating type identities are required for mating.
Receptors, Mating Factor
A family of pheromone receptors that were initially discovered in SACCHAROMYCES CEREVISIAE as proteins necessary for fungal conjugation. Each mating factor receptor is expressed in HAPLOID CELLS of a single mating type.
Animals, Inbred Strains
Animals produced by the mating of littermates or siblings over multiple generations. The resultant strain of animals is virtually identical genotypically. Highly inbred animal lines allow the study of certain traits in a relatively pure form. (Segen, Dictionary of Modern Medicine, 1992)
Killer Factors, Yeast
Protein factors released from one species of YEAST that are selectively toxic to another species of yeast.
3t3 Cells
Cell lines whose original growing procedure consisted being transferred (T) every 3 days and plated at 300,000 cells per plate (J Cell Biol 17:299-313, 1963). Lines have been developed using several different strains of mice. Tissues are usually fibroblasts derived from mouse embryos but other types and sources have been developed as well. The 3T3 lines are valuable in vitro host systems for oncogenic virus transformation studies, since 3T3 cells possess a high sensitivity to CONTACT INHIBITION.
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