Advertisement

More hypotension in patients taking antihypertensives preoperatively during shoulder surgery in the beach chair position.

10:34 EDT 22nd May 2013 | BioPortfolio

Summary of "More hypotension in patients taking antihypertensives preoperatively during shoulder surgery in the beach chair position."


PURPOSE:
Hypotension is common in patients undergoing surgery in the sitting position under general anesthesia, and the risk may be exacerbated by the use of antihypertensive drugs taken preoperatively. The purpose of this study was to compare hypotensive episodes in patients taking antihypertensive medications with normotensive patients during shoulder surgery in the beach chair position.
METHODS:
Medical records of all patients undergoing shoulder arthroscopy during a 44-month period were reviewed retrospectively. The primary endpoint was the number of moderate hypotensive episodes (systolic blood pressure ≤ 85 mmHg) during the intraoperative period. Secondary endpoints included the frequency of vasopressor administration, total dose of vasopressors, and fluid administered. Values are expressed as mean (standard deviation).
RESULTS:
Of 384 patients who underwent shoulder surgery, 185 patients were taking no antihypertensive medication, and 199 were on at least one antihypertensive drug. The antihypertensive medication group had more intraoperative hypotensive episodes [1.7 (2.2) vs 1.2 (1.8); P = 0.01] and vasopressor administrations. Total dose of vasopressors and volume of fluids administered were similar between groups. The timing of the administration of angiotensin-converting enzyme inhibitors and of angiotensin receptor antagonists (≤ 10 hr vs > 10 hr before surgery) had no impact on intraoperative hypotension.
CONCLUSIONS:
Preoperative use of antihypertensive medication was associated with an increased incidence of intraoperative hypotension. Compared with normotensive patients, patients taking antihypertensive drugs preoperatively are expected to require vasopressors more often to maintain normal blood pressure.

Affiliation

Department of Anesthesiology, Mayo Clinic in Arizona, 5777 E Mayo Blvd, Phoenix, AZ, 85054, USA, trentman.terrence@mayo.edu.

Journal Details

This article was published in the following journal.

Name: Canadian journal of anaesthesia = Journal canadien d'anesthesie
ISSN: 1496-8975
Pages:

Links

Medical and Biotech [MESH] Definitions

Shoulder Pain

Unilateral or bilateral pain of the shoulder. It is often caused by physical activities such as work or sports participation, but may also be pathologic in origin.

Test Taking Skills

Skills and strategies, unrelated to the traits a test is intended to measure, that may increase test takers' scores -- may include the effects of coaching or experience in taking tests. (ERIC Thesaurus)

Veratrum

A plant genus of the family LILIACEAE with roots that contain VERATRUM ALKALOIDS used as emetics, parasiticides, antihypertensives. It is the main ingredient of Boicil.

Ganglionic Blockers

Agents having as their major action the interruption of neural transmission at nicotinic receptors on postganglionic autonomic neurons. Because their actions are so broad, including blocking of sympathetic and parasympathetic systems, their therapeutic use has been largely supplanted by more specific drugs. They may still be used in the control of blood pressure in patients with acute dissecting aortic aneurysm and for the induction of hypotension in surgery.

Hypotension, Orthostatic

A significant drop in BLOOD PRESSURE after assuming a standing position. Orthostatic hypotension is a finding, and defined as a 20-mm Hg decrease in systolic pressure or a 10-mm Hg decrease in diastolic pressure 3 minutes after the person has risen from supine to standing. Symptoms generally include DIZZINESS, blurred vision, and SYNCOPE.

PubMed Articles [ 5957 Associated PubMed Articles listed on BioPortfolio]

Cerebral oximetry desaturation during shoulder surgery performed in a sitting position under regional anesthesia.

PURPOSE: Hypotension in the sitting position may reduce cerebral perfusion and oxygenation. We prospectively determined the incidence of cerebral oximetry (rSO2) desaturation in seated patients underg...

Arthroscopic Repair of Anterosuperior Rotator Cuff Tears Combined With Open Biceps Tenodesis.

PURPOSE: The purpose of this study was to look at the functional outcomes of arthroscopic repair of anterosuperior rotator cuff tears with open biceps tenodesis when indicated. METHODS: We retrospecti...

Minor or occult shoulder instability: an intra-articular pathology presenting with extra-articular subacromial impingement symptoms.

PURPOSE: Disruption in the balance of shoulder stability can produce a widely varied spectrum of clinical symptoms, ranging from minor shoulder instability to frank shoulder dislocation, followed by r...

The impact of a change in hypertension management guidelines on diuretic use in Japan: trends in antihypertensive drug prescriptions from 2005 to 2011.

The Japanese Society of Hypertension (JSH) updated its hypertension management guidelines in 2009. One of the most significant changes with respect to the 2004 version was the stance towards the use o...

Reverse Total Shoulder Arthroplasty Improves Function in Cuff Tear Arthropathy.

BACKGROUND: Early failure due to glenoid loosening with anatomic total shoulder arthroplasty in patients with severe rotator cuff deficiency led to the development of the reverse ball-and-socket shoul...

Clinical Trials [ 1112 Associated Clinical Trials listed on BioPortfolio]

Can Augmentation Index (AIx) be Used to Predict Hypotension After Spinal Anesthesia?

A fall in blood pressure (hypotension) occurs in one third of spinal anesthetics administered to pregnant patients undergoing cesarean delivery. However, predicting which patients will ex...

Interaction Between Antihypertensives and Non-Steroidal Anti-Inflammatory Drugs (NSAIDs)

NSAIDs may increase blood pressure and blunt the effects of many antihypertensives. Members of these drug classes differ in their propensity to such an interaction.

Study of the Effect of Neck Treatment on Shoulder Impingement

The purpose of this pilot study is to conduct research to determine the most effective physical therapy treatment for a condition called shoulder impingement. This condition occurs when t...

Evaluation of M40403 for the Prevention of Dose Limiting Toxicities of High Dose IL-2

The clinical use of IL-2 is currently limited by development of dose-dependent hypotension (systolic blood pressure (SBP) < 90 mm Hg). The overall outcome is constant across sites with 20...

Safety and Benefit Study of Droxidopa to Treat Patients With Intradialytic Hypotension

In clinical trials in Japan, droxidopa has been shown to be effective in affecting blood pressure changes upon orthostatic challenge in patients with autonomic dysfunction, as well as redu...

Search BioPortfolio:
Advertisement
Advertisement