Salivary gland biopsy: a comprehensive review of techniques and related complications.
Summary of "Salivary gland biopsy: a comprehensive review of techniques and related complications."
Objective. This study proposes a revision of the literature on the current techniques employed in salivary gland biopsy. Methods. A systematic review of the literature between January 1990 and January 2010 was conducted using MEDLINE, Embase and the Cochrane Central Register of Controlled Trials. The search terms were: 'biopsy AND parotid AND Sjögren'; 'biopsy AND sublingual salivary gland AND Sjögren'; 'biopsy AND minor salivary gland AND Sjögren'; 'biopsy AND labial salivary gland AND Sjögren' and 'biopsy AND salivary glands AND connective disorders'. Results. No study reporting submandibular salivary gland biopsy was found; 3 studies reported sublingual salivary gland biopsy; 1 study reported palate biopsy; 4 studies reported parotid gland biopsy and 21 studies reported minor salivary gland biopsy. Conclusion. Biopsy of salivary glands must be performed as last investigation and only when the other items are not complete enough to satisfy the diagnosis. The knowledge of complications and sequelae may be useful in order to minimize the risk.
Department of Head and Neck Pathology, Second University of Naples, Naples, Italy.
This article was published in the following journal.
Name: Rheumatology (Oxford, England)
- PubMed Source: http://www.ncbi.nlm.nih.gov/pubmed/20660500
- DOI: http://dx.doi.org/10.1093/rheumatology/keq225
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Medical and Biotech [MESH] Definitions
Calculi occurring in a salivary gland. Most salivary gland calculi occur in the submandibular gland, but can also occur in the parotid gland and in the sublingual and minor salivary glands.
Glands that secrete SALIVA in the MOUTH. There are three pairs of salivary glands (PAROTID GLAND; SUBLINGUAL GLAND; SUBMANDIBULAR GLAND).
A fistula between a salivary duct or gland and the cutaneous surface of the oral cavity.
A benign, slow-growing tumor, most commonly of the salivary gland, occurring as a small, painless, firm nodule, usually of the parotid gland, but also found in any major or accessory salivary gland anywhere in the oral cavity. It is most often seen in women in the fifth decade. Histologically, the tumor presents a variety of cells: cuboidal, columnar, and squamous cells, showing all forms of epithelial growth. (Dorland, 27th ed)
Tumors or cancer of the SALIVARY GLANDS.