1,2-Bis(pyridin-2-ylmethyl)sulfanylethane and its dimorphic hydrochloride salt.
Summary of "1,2-Bis(pyridin-2-ylmethyl)sulfanylethane and its dimorphic hydrochloride salt."
Although having been described as a liquid in the literature for 41 years, 1,2-bis[(pyridin-2-ylmethyl)sulfanyl]ethane, C(14)H(16)N(2)S(2), (I), has now been obtained as monoclinic crystals via a new and convenient method of purification. Molecules of (I) are located on crystallographic inversion centres and are held together by C-H...N and C-H...S interactions, resulting in the formation of a three-dimensional network structure. In addition, two polymorphs of the corresponding hydrochloride salt, 2-[({2-[(pyridin-1-ium-2-ylmethyl)sulfanyl]ethyl}sulfanyl)methyl]pyridin-1-ium dichloride, C(14)H(18)N(2)S(2)(2+)·2Cl(-), (II) and (III), have been isolated. Molecules of (II) and (III) have similar conformations and are located on inversion centres. Both polymorphs form three-dimensional networks through N-H...Cl, C-H...Cl and C-H...S interactions. The structure of (III) displays voids of 35 Å(3).
Affiliation
Department of Physics and Chemistry, University of Southern Denmark, Campusvej 55, 5230 Odense M, Denmark.
Journal Details
This article was published in the following journal.
Name: Acta crystallographica. Section C, Crystal structure communications
ISSN: 1600-5759
Pages: o354-8
Links
- PubMed Source: http://www.ncbi.nlm.nih.gov/pubmed/21881186
- DOI: http://dx.doi.org/10.1107/S0108270111027867
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A bile salt formed in the liver by conjugation of deoxycholate with taurine, usually as the sodium salt. It is used as a cholagogue and choleretic, also industrially as a fat emulsifier.
Glycochenodeoxycholic Acid
A bile salt formed in the liver from chenodeoxycholate and glycine, usually as the sodium salt. It acts as a detergent to solubilize fats for absorption and is itself absorbed. It is a cholagogue and choleretic.
Glycodeoxycholic Acid
A bile salt formed in the liver by conjugation of deoxycholate with glycine, usually as the sodium salt. It acts as a detergent to solubilize fats for absorption and is itself absorbed. It is used as a cholagogue and choleretic.
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