Tethered cord: natural history, surgical outcome and risk for Chiari malformation 1 (CM1) : A review of 110 detethering.

23:30 EDT 16th September 2014 | BioPortfolio

Summary of "Tethered cord: natural history, surgical outcome and risk for Chiari malformation 1 (CM1) : A review of 110 detethering."

The surgical results of this series of occult spina bifida seem better than the natural history registered in the long pre-operative period in terms of neurological deterioration. The major contribution to this result is attributed to neurophysiological monitoring that lowers the risks of permanent damage and increases the percentage of effective detethering. The present series of TCS, due to conus and filar lipoma, documents that CM1 is a really rare association occurring in less than 6% of the patients, despite the low position of conus. The detethering procedure did not influence the tonsillar position, thus excluding the correlation between the tethering and the tonsillar descent. The genetic alteration documented in a girl reinforces the hypothesis of a rare complex polymaformative picture deserving multiple procedures according to the prevailing clinical symptoms.

Affiliation

Department of Neurosurgery, Fondazione Istituto Neurologico "Carlo Besta", Via Celoria 11, 20133, Milan, Italy, lvalentini@istituto-besta.it.

Journal Details

This article was published in the following journal.

Name: Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiol
ISSN: 1590-3478
Pages:

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