Perceptions and attitudes of Jordanian paediatricians towards off-label paediatric prescribing.
Summary of "Perceptions and attitudes of Jordanian paediatricians towards off-label paediatric prescribing."
Objective To assess current experiences and attitudes of hospital based paediatricians towards off-label medicine prescribing. Setting Paediatric hospital wards and out-patient clinics. Design A prospective, questionnaire based study. Results A 30 item questionnaire was sent to 300 hospital based paediatricians and 250 (83%) were returned completed. Over 69% of responders were familiar with the term off-label medicines. However, only 28% were knowingly prescribing off-label medicines to children. The majority of respondents (90%) expressed concerns about the safety and efficacy of off-label medicines. Only 15% had observed Adverse Drug Reactions, and 31% a treatment failure. The vast majority of respondents (83%) did not obtain informed consent or tell parents they were prescribing off label medicines to their children. Conclusions Off-label prescribing of medicines to children is a familiar concept to the majority of paediatricians in Jordan although only a smaller number are aware that it is common in their practice. Respondents showed concern about off label prescribing, although the majority do not consider it necessary to inform parents. More comprehensive research is needed in this area in Jordan and other Middle Eastern countries.
Affiliation
Department of Clinical Pharmacy, Faculty of Pharmacy, Jordan University of Science and Technology, Irbid, 22110, Jordan, tlmukattash@just.edu.jo.
Journal Details
This article was published in the following journal.
Name: International journal of clinical pharmacy
ISSN: 2210-7711
Pages:
Links
- PubMed Source: http://www.ncbi.nlm.nih.gov/pubmed/21952953
- DOI: http://dx.doi.org/10.1007/s11096-011-9569-z
Medical and Biotech [MESH] Definitions
Off-label Use
The practice of prescribing or using a drug outside the scope of the drug's official approved label as designated by a regulatory agency concerning the treatment of a particular disease or condition.
Inappropriate Prescribing
The practice of prescribing medications in a manner that poses more risk than benefit, particularly where safer alternatives exist.
Health Knowledge, Attitudes, Practice
Knowledge, attitudes, and associated behaviors which pertain to health-related topics such as PATHOLOGIC PROCESSES or diseases, their prevention, and treatment. This term refers to non-health workers and health workers (HEALTH PERSONNEL).
Ibotenic Acid
A neurotoxic isoxazole (similar to KAINIC ACID and MUSCIMOL) found in AMANITA mushrooms. It causes motor depression, ataxia, and changes in mood, perceptions and feelings, and is a potent excitatory amino acid agonist.
Electronic Prescribing
The use of COMPUTER COMMUNICATION NETWORKS to store and transmit medical PRESCRIPTIONS.
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