Use of extracorporeal life support in adults with severe acute respiratory failure.
Summary of "Use of extracorporeal life support in adults with severe acute respiratory failure."
Extracorporeal membrane oxygenation (ECMO) is a recognized and accepted therapeutic option in the treatment of neonatal and pediatric respiratory failure. However, early studies in adults did not demonstrate a survival benefit associated with the utilization of ECMO for severe acute respiratory failure. Despite this historical lack of benefit, use of ECMO in adult patients has seen a recent resurgence. Local successes and a recently published randomized trial have both demonstrated promising results in an adult population with high baseline mortality and limited therapeutic options. This article will review the history of ECMO use for respiratory failure; investigate the driving forces behind the latest surge in interest in ECMO for adults with refractory severe acute respiratory failure; and describe potential applications of ECMO that will likely increase in the near future.
Affiliation
Duke University Medical Center, Division of Pediatric Critical Care Medicine, Durham, NC, USA.
Journal Details
This article was published in the following journal.
Name: Expert review of respiratory medicine
ISSN: 1747-6356
Pages: 627-33
Links
- PubMed Source: http://www.ncbi.nlm.nih.gov/pubmed/21955233
- DOI: http://dx.doi.org/10.1586/ers.11.57
Medical and Biotech [MESH] Definitions
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Respiratory support system used primarily with rates of about 100 to 200/min with volumes of from about one to three times predicted anatomic dead space. Used to treat respiratory failure and maintain ventilation under severe circumstances.
Life Support Systems
Systems that provide all or most of the items necessary for maintaining life and health. Provisions are made for the supplying of oxygen, food, water, temperature and pressure control, disposition of carbon dioxide and body waste. The milieu may be a spacecraft, a submarine, or the surface of the moon. In medical care, usually under hospital conditions, LIFE SUPPORT CARE is available. (From Webster's New Collegiate Dictionary)
Sars Virus
A species of CORONAVIRUS causing atypical respiratory disease (SEVERE ACUTE RESPIRATORY SYNDROME) in humans. The organism is believed to have first emerged in Guangdong Province, China, in 2002. The natural host is the Chinese horseshoe bat, RHINOLOPHUS sinicus.
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Married persons, i.e., husbands and wives, or partners. Domestic partners, or spousal equivalents, are two adults who have chosen to share their lives in an intimate and committed relationship, reside together, and share a mutual obligation of support for the basic necessities of life.
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