Quetiapine (Seroquel) and QT-interval prolongation.

14:48 EDT 24th October 2014 | BioPortfolio

Summary of "Quetiapine (Seroquel) and QT-interval prolongation."

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This article was published in the following journal.

Name: The Medical letter on drugs and therapeutics
ISSN: 1523-2859
Pages: 79-80

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PubMed Articles [2302 Associated PubMed Articles listed on BioPortfolio]

The Comparative Cardiac Effects of Haloperidol and Quetiapine: Parsing a Review.

A potential adverse effect of many non-cardiac drugs, including certain psychotropic medications, is an abnormally prolonged corrected QT (QTc) interval and an increased risk of developing torsade de ...

Effectiveness of a Clinical Decision Support System for Reducing the Risk of QT Interval Prolongation in Hospitalized Patients.

prolongation was developed and implemented using information extracted from patients' electronic medical records. When a drug associated with torsades de pointes was prescribed to a patient at moderat...

A Case of Drug-Induced Interstitial Pneumonia Potentially Related to Quetiapine (Seroquel) Therapy for Behavioral and Psychological Symptoms.

Quetiapine is regarded as an effective and safe treatment for delirium. An 82-year-old man presented with a 1-week history of violent behavior and dizziness accompanied by weakness on the left side of...

Methadone, QTc prolongation and torsades de pointes: Current concepts, management and a hidden twist in the tale?

Methadone is a drug that has found widespread utility in the management of opioid addiction and pain. Along with its popularity, methadone has also earned an infamous reputation for causing prolongati...

Torsade de pointes in liver transplantation recipient after induction of general anesthesia: a case report.

Torsade de pointes (TdP) is an uncommon and specific form of polymorphic ventricular tachycardia, associated with a prolonged QT interval. Prolongation of the QT interval is the most widely recognized...

Clinical Trials [491 Associated Clinical Trials listed on BioPortfolio]

Seroquel- Agitation Associated With Dementia

The purpose of this study is to determine how safe and effective Seroquel (quetiapine fumarate) is compared to placebo (a non-drug tablet) for a period of up to 10 weeks in the treatment ...

Positron Emission Tomography (PET) Study With [11C]Raclopride to Determine Central D2 Dopamine Occupancy of SEROQUEL

The aim of this study is to relate pharmacokinetics of two different formulations of quetiapine to PET measured receptor occupancy in the brains of healthy subjects.

Phase III/Seroquel SR Bipolar Depression Monotherapy - US

The purpose of this study is to determine the safety and efficacy of sustained-release quetiapine fumarate (Seroquel®) in the treatment of patients with Acute Bipolar Depression for 8 we...

Study of the Efficacy and Safety of Quetiapine Fumarate Extended Release (Seroquel XR)

This is an 8-week, multi-centre, Open-label, non-comparative study to evaluate the efficacy and safety of Quetiapine XR with daily dose 400mg-800mg used as mono-therapy in the treatment of...

Phase 3 /Seroquel SR Acute Mania Monotherapy - US

The purpose of this study is to determine the safety and efficacy of sustained-release quetiapine fumarate (Seroquel®) in the treatment of patients with Acute Bipolar Mania for 3 weeks. ...

Medical and Biotech [MESH] Definitions

Relief of PAIN, without loss of CONSCIOUSNESS, through ANALGESIC AGENTS administered by the patients. It has been used successfully to control POSTOPERATIVE PAIN, during OBSTETRIC LABOR, after BURNS, and in TERMINAL CARE. The choice of agent, dose, and lockout interval greatly influence effectiveness. The potential for overdose can be minimized by combining small bolus doses with a mandatory interval between successive doses (lockout interval).

The proportion of survivors in a group, e.g., of patients, studied and followed over a period, or the proportion of persons in a specified group alive at the beginning of a time interval who survive to the end of the interval. It is often studied using life table methods.

A form of ventricular pre-excitation characterized by a normal PR interval and a long QRS interval with an initial slow deflection (delta wave). In this syndrome, the atrial impulse travel to the ventricle via the Mahaim fibers which connect ATRIOVENTRICULAR NODE directly to the right ventricle wall (nodoventricular pathway) or to the RIGHT BUNDLE BRANCH OF HIS (nodofascicular pathway).

A form of ventricular pre-excitation characterized by a short PR interval and a long QRS interval with a delta wave. In this syndrome, atrial impulse conducts to the HEART VENTRICLES via an accessory pathway located between the wall of the right or left atria and the ventricles, known as the bundle of Kent. The inherited form can be caused by mutation of PRKAG2 gene encoding a gamma-2 regulatory subunit of AMP-activated protein kinase.

Legal documents that are declarations of individuals' wishes regarding the disposal of their property or estate after death; esp: written instruments, legally executed, by which dispositions are made of estates. LIVING WILLS are written declarations regarding prolongation of life by extraordinary means.

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