A convergent approach to polycyclic aromatic hydrocarbons.
Summary of "A convergent approach to polycyclic aromatic hydrocarbons."
A new concise route to Polycyclic Aromatic Hydrocarbons (PAHs) through radical addition and cyclisation of xanthates is described.
Affiliation
Laboratoire de Synthèse Organique, CNRS UMR 7652, Ecole Polytechnique, F-91128 Palaiseau, France. zard@poly.polytechnique.fr.
Journal Details
This article was published in the following journal.
Name: Chemical communications (Cambridge, England)
ISSN: 1364-548X
Pages: 12185-7
Links
- PubMed Source: http://www.ncbi.nlm.nih.gov/pubmed/21998824
- DOI: http://dx.doi.org/10.1039/c1cc15095b
Medical and Biotech [MESH] Definitions
Bay-region, Polycyclic Aromatic Hydrocarbon
A concave exterior region on some POLYCYCLIC AROMATIC HYDROCARBONS that have three phenyl rings in a non-linear arrangement.
Polycyclic Hydrocarbons, Aromatic
A major group of unsaturated cyclic hydrocarbons containing two or more rings. The vast number of compounds of this important group, derived chiefly from petroleum and coal tar, are rather highly reactive and chemically versatile. The name is due to the strong and not unpleasant odor characteristic of most substances of this nature. (From Hawley's Condensed Chemical Dictionary, 12th ed, p96)
Cytochrome P-450 Cyp1a1
A liver microsomal cytochrome P-450 monooxygenase capable of biotransforming xenobiotics such as polycyclic hydrocarbons and halogenated aromatic hydrocarbons into carcinogenic or mutagenic compounds. They have been found in mammals and fish. This enzyme, encoded by CYP1A1 gene, can be measured by using ethoxyresorufin as a substrate for the ethoxyresorufin O-deethylase activity.
Receptors, Aryl Hydrocarbon
Cytoplasmic proteins that bind certain aryl hydrocarbons, translocate to the nucleus, and activate transcription of particular DNA segments. AH receptors are identified by their high-affinity binding to several carcinogenic or teratogenic environmental chemicals including polycyclic aromatic hydrocarbons found in cigarette smoke and smog, heterocyclic amines found in cooked foods, and halogenated hydrocarbons including dioxins and polychlorinated biphenyls. No endogenous ligand has been identified, but an unknown natural messenger with a role in cell differentiation and development is suspected.
Creosote
A greasy substance with a smoky odor and burned taste created by high temperature treatment of BEECH and other WOOD; COAL TAR; or resin of the CREOSOTE BUSH. It contains CRESOLS and POLYCYCLIC AROMATIC HYDROCARBONS which are CARCINOGENS. It has been widely used as wood preservative and in PESTICIDES and had former use medicinally in DISINFECTANTS; LAXATIVES; and DERMATOLOGIC AGENTS.
PubMed Articles
Synthesis of uniformly (13)C-labeled polycyclic aromatic hydrocarbons.
Convergent synthetic pathways were devised for efficient synthesis of a series of uniformly (13)C labeled polycyclic aromatic hydrocarbons de novo from U-(13)C-benzene and other simple commercially-av...
Polycyclic aromatic hydrocarbons (PAHs) in a coal tar standard reference material-SRM 1597a updated.
SRM 1597 Complex Mixture of Polycyclic Aromatic Hydrocarbons from Coal Tar, originally issued in 1987, was recently reanalyzed and reissued as SRM 1597a with 34 certified, 46 reference, and 12 informa...
Direct Arylation of Polycyclic Aromatic Hydrocarbons through Palladium Catalysis.
We have discovered that the combination of Pd(OAc)(2)/o-chloranil can catalyze the direct C-H bond arylation of polycyclic aromatic hydrocarbons (PAHs) with arylboroxins that occurs selectively at the...
This paper describes a novel method of sample preparation for the determination of trace concentrations of polycyclic aromatic hydrocarbons (PAHs) in high-boiling petroleum products. Limits of quantit...
New polycyclic borazine species.
The new polycyclic borazines B(2){1,2-N(2)C(6)H(4)}(2){B(2)(NMe(2))(2)}(2), B(2){1,8-N(2)naph}(2){B(2)(NMe(2))(2)}(2) and B(2)(NPh)(4){B(2)(NMe(2))(2)}(2) have been prepared from diborate(4) anions an...
Clinical Trials
Aromatic Amino Acid Metabolism in the Pathogenesis of Kwashiorkor
This research may explain whether a shortage of three special compounds called aromatic amino acids is responsible for the severe illness and high death rate of children with the kwashiork...
Treatment of Acute Pharyngo-Tonsillitis With Essential Oils of Aromatic Plants
This randomized, double blind, parallel group study, compared the efficacy of spray containing aromatic essential oils of some herbal plants, against placebo in the treatment of patients w...
Interdisciplinary Case-Control Study of Bladder Cancer in Spain
The incidence rate of bladder cancer in the Barcelona area of Spain is almost identical to that of the U.S. Cigarette smoking has been identified as the most significant risk factor for b...
Posterolateral Surgical Approach Compared With Modified Lateral Approach
It has been reported that the operative approaches have an effect on clinical outcome in total hip arthroplasty. The purpose of this prospective study was to compare clinical and radiologi...
Antiretroviral Treatment Simplified Follow-up Management Assessment (ANRS 12110 STRATALL)
Access to antiretroviral therapy (ART) is still limited in Africa (11% of patients in immediate need in June 2005). Face to the scope of the need and the constraints (unavailability and co...
