Evaluation of two sirolimus assays using the ARCHITECT-i1000((R)) CMIA or RxL((R)) ACMIA methods in comparison with the IMx((R)) MEIA method.
Summary of "Evaluation of two sirolimus assays using the ARCHITECT-i1000((R)) CMIA or RxL((R)) ACMIA methods in comparison with the IMx((R)) MEIA method."
No Summary Available
Affiliation
Department of Biochemistry, Lapeyronie Hospital, Montpellier, France.
Journal Details
This article was published in the following journal.
Name: Clinical chemistry and laboratory medicine : CCLM / FESCC
ISSN: 1434-6621
Pages:
Links
- PubMed Source: http://www.ncbi.nlm.nih.gov/pubmed/20666697
- DOI: http://dx.doi.org/10.1515/CCLM.2010.288
Medical and Biotech [MESH] Definitions
Sirolimus
A macrolide compound obtained from Streptomyces hygroscopicus that acts by selectively blocking the transcriptional activation of cytokines thereby inhibiting cytokine production. It is bioactive only when bound to IMMUNOPHILINS. Sirolimus is a potent immunosuppressant and possesses both antifungal and antineoplastic properties.
High-throughput Screening Assays
Rapid methods of measuring the effects of an agent in a biological or chemical assay. The assay usually involves some form of automation or a way to conduct multiple assays at the same time using sample arrays.
Evaluation Studies As Topic
Studies determining the effectiveness or value of processes, personnel, and equipment, or the material on conducting such studies. For drugs and devices, CLINICAL TRIALS AS TOPIC; DRUG EVALUATION; and DRUG EVALUATION, PRECLINICAL are available.
Cell Migration Assays, Leukocyte
Assays that measure the rate of migration of LEUKOCYTES. They may involve a variety of techniques such as measuring the movement of leukocytes through substrates such as AGAROSE gels or the rate of exit of cells from a glass capillary.
Program Evaluation
Studies designed to assess the efficacy of programs. They may include the evaluation of cost-effectiveness, the extent to which objectives are met, or impact.
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