Duration of clopidogrel therapy with drug-eluting stents.
Summary of "Duration of clopidogrel therapy with drug-eluting stents."
To the Editor: In their article about the duration of dual antiplatelet therapy after implantation of drug-eluting stents, Park and colleagues (April 15 issue)(1) report that the use of extended dual antiplatelet therapy in patients who had received drug-eluting stents was not significantly more effective than aspirin monotherapy in reducing the rate of myocardial infarction or death from cardiac causes. Yet the rate of a composite of myocardial infarction, stroke, or death from any cause was nearly significantly higher in patients receiving extended dual antiplatelet therapy than in those receiving aspirin alone. These results are unpredictable and thus are difficult . . .
Affiliation
Journal Details
This article was published in the following journal.
Name: The New England journal of medicine
ISSN: 1533-4406
Pages: 488-90
Links
- PubMed Source: http://www.ncbi.nlm.nih.gov/pubmed/20666628
- DOI: http://dx.doi.org/10.1056/NEJMc1005624
Medical and Biotech [MESH] Definitions
Drug-eluting Stents
Stents that are covered with materials that are embedded with chemicals that are gradually released into the surrounding milieu.
Drug Therapy, Combination
Therapy with two or more separate preparations given for a combined effect.
Drug Therapy, Computer-assisted
Adjunctive computer programs in providing drug treatment to patients.
Chemotherapy, Adjuvant
Drug therapy given to augment or stimulate some other form of treatment such as surgery or radiation therapy. Adjuvant chemotherapy is commonly used in the therapy of cancer and can be administered before or after the primary treatment.
Drug Labeling
Use of written, printed, or graphic materials upon or accompanying a drug container or wrapper. It includes contents, indications, effects, dosages, routes, methods, frequency and duration of administration, warnings, hazards, contraindications, side effects, precautions, and other relevant information.
PubMed Articles
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Human coronary bare-metal stents (BMS) and drug-eluting stents (DES) from autopsy cases with implant duration >30 days were examined for the presence of neointimal atherosclerotic disease.
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Safety and Efficacy of Six Months Dual Antiplatelet Therapy After Drug-Eluting Stenting
The purpose of this study is to determine whether a 6 month duration of clopidogrel therapy after DES implantation is not inferior to that of a 12 month therapy.
Sirolimus Eluting Stents in Complex Coronary Lesions (SCANDSTENT)
The purpose of this study is to evaluate the clinical and angiographic outcome of implantation of stents eluting or not eluting Sirolimus in patients with complex coronary artery lesions s...
