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For the first time, the superoxide anion radical was formed by electrochemical reduction of oxygen and detected in situ by EPR spectroscopy without changing the temperature. The spin susceptibilities of solid superoxide solutions were measured between 280 and 4 K showing Curie behavior. The EPR results were explained in the frame of an ion association and support the formation of a loose ion pair between the superoxide anion radical and the potassium crown ether complex. An alternative explanation for the large EPR line width of the superoxide anion radical at higher temperatures is given.
Leibniz Institute for Solid State and Materials Research IFW Dresden , PF 270116, D-01171 Dresden, Germany.
This article was published in the following journal.
Name: The journal of physical chemistry. B
The mechanism of action of sulforaphane as a scavenger of superoxide radical anion (O2•‾) and hydrogen peroxide (H2O2) has been investigated using density functional theory in both gas phase and a...
This contribution describes the trapping of the hydroperoxyl radical at a pH of 4 during turnover of wild-type oxalate decarboxylase and its T165V mutant using the spin trap BMPO. Radicals were detect...
[This corrects the article DOI: 10.1371/journal.pone.0115466.].
It is currently accepted that superoxide anion (O2•-) is an important mediator in pain and inflammation. The role of superoxide anion in pain and inflammation has been mainly determined indirectly b...
Inhibition of tumor necrosis factor-alpha (TNFα) and superoxide anion production reduces inflammation and pain. The present study investigated whether superoxide anion-induced pain depends on TNFα s...
When exposed to oxygen immediately after birth, newborns suffer from an oxidative stress with a significant decrease in serum concentration of the anti-oxidant enzyme superoxide dismutase....
The purpose of this study is to conduct a Phase I clinical trial involving in situ RTVP-1 gene therapy for prostate cancer. We will conduct necessary safety evaluations on a new adenoviru...
Radical prostatectomy and radical radiation therapy remain the standard treatment approaches for patients with clinically localized prostate cancer (T1, T2).Radical prostatectomy is most e...
The investigator intends to review retrospective de-identified data of patients who have had Laparoscopic Radical Cystectomies by the Department of Urology at UCIMC.
The purpose of this study is to determine whether increasing cardiac output by a combination of intravenous fluids and inotropic drugs can reduce mortality and morbidity in radical cystect...
A flavoprotein enzyme that catalyzes the univalent reduction of OXYGEN using NADPH as an electron donor to create SUPEROXIDE ANION. The enzyme is dependent on a variety of CYTOCHROMES. Defects in the production of superoxide ions by enzymes such as NADPH oxidase result in GRANULOMATOUS DISEASE, CHRONIC.
An oxidoreductase that catalyzes the reaction between superoxide anions and hydrogen to yield molecular oxygen and hydrogen peroxide. The enzyme protects the cell against dangerous levels of superoxide. EC 126.96.36.199.
A potent oxidant synthesized by the cell during its normal metabolism. Peroxynitrite is formed from the reaction of two free radicals, NITRIC OXIDE and the superoxide anion (SUPEROXIDES).
A technique that labels specific sequences in whole chromosomes by in situ DNA chain elongation or PCR (polymerase chain reaction).
The univalent radical OH. Hydroxyl radical is a potent oxidizing agent.