Ganodone, a Bioactive Benzofuran from the Fruiting Bodies of Ganoderma tsugae.
Summary of "Ganodone, a Bioactive Benzofuran from the Fruiting Bodies of Ganoderma tsugae."
Extracts of Ganoderma tsugae, also known as the Hemlock varnish shelf mushroom, and related Reishi mushrooms are well documented in traditional Chinese medicine. Several Ganoderma sp. are currently cultivated for use in coffee, teas, and dietary supplements. We now report on the isolation and characterization of an unprecedented benzofuran, ganodone (1), from the fruiting bodies of mature growth G. tsugae. This discovery provides a key next step in evaluating the active components in their associated herbal supplements.
Affiliation
Xenobe Research Institute, P.O. Box 3052, San Diego, California 92163-1052, United States.
Journal Details
This article was published in the following journal.
Name: Journal of natural products
ISSN: 1520-6025
Pages: 2045-51
Links
- PubMed Source: http://www.ncbi.nlm.nih.gov/pubmed/21939217
- DOI: http://dx.doi.org/10.1021/np200361y
Medical and Biotech [MESH] Definitions
Fruiting Bodies, Fungal
The fruiting 'heads' or 'caps' of FUNGI, which as a food item are familiarly known as MUSHROOMS, that contain the FUNGAL SPORES.
Ganoderma
A genus of fungi in the family Ganodermataceae, order POLYPORALES, containing a dimitic hyphal system. It causes a white rot, and is a wood decomposer. Ganoderma lucidum (REISHI) is used in traditional Chinese medicine (MEDICINE, CHINESE TRADITIONAL).
Agaricales
An extensive order of basidiomycetous fungi whose fruiting bodies are commonly called mushrooms.
Flammulina
A genus of mushrooms in the family Tricholomataceae, whose species are characterized by a slimy cap (FRUITING BODIES, FUNGAL).
Pycnoporus
A genus of basidiomyceteous fungi in the family POLYPORACEAE. The species all contain bright orange, bracket-like fruiting bodies.
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