Advertisement

The use of high doses of OROS hydromorphone in an acute palliative care unit.

15:27 EDT 23rd May 2013 | BioPortfolio

Summary of "The use of high doses of OROS hydromorphone in an acute palliative care unit."

Abstract Objectives: To characterize patients who received high doses of OROS hydromorphone (OROD-HY), a retrospective study of patients admitted in an acute pain relief and palliative care unit for a period of two years (from June 2009 to June 2011) was performed. Methods: Globally, 79 patients were prescribed OROS-HY during admission at mean maximum doses of 68?mg/day (?42). Twenty-two patients were switched from other opioids to OROS-HY and 16 patients were switched from OROS-HY to other opioids. Sixty-three patients were discharged home with a prescription of OROS-HY with doses of 53?mg/day (?44). Doses were significantly lower in older patients (p?

Affiliation

Journal Details

This article was published in the following journal.

Name: Current medical research and opinion
ISSN: 1473-4877
Pages:

Links

Medical and Biotech [MESH] Definitions

Coronary Care Units

The hospital unit in which patients with acute cardiac disorders receive intensive care.

Palliative Care

Care alleviating symptoms without curing the underlying disease. (Stedman, 25th ed)

Apache

An acronym for Acute Physiology and Chronic Health Evaluation, a scoring system using routinely collected data and providing an accurate, objective description for a broad range of intensive care unit admissions, measuring severity of illness in critically ill patients.

Tachyphylaxis

Rapidly decreasing response to a drug or physiologically active agent after administration of a few doses. In immunology, it is the rapid immunization against the effect of toxic doses of an extract or serum by previous injection of small doses. (Dorland, 28th ed)

Hospices

Facilities or services which are especially devoted to providing palliative and supportive care to the patient with a terminal illness and to the patient's family.

PubMed Articles [ 26538 Associated PubMed Articles listed on BioPortfolio]

Use of OROS(®) hydromorphone in the treatment of osteoarthritis and osteoporosis: A pooled analysis of three non-interventional studies focusing on different starting doses.

OBJECTIVE: To determine the effect of a lower starting dose of OROS® hydromorphone compared with a higher starting dose. DESIGN: Data from the first 15 days of treatment were compared in a combined a...

Results of a Double-blind, Placebo-controlled, Fixed-dose Assessment of Once-daily OROS(®) Hydromorphone ER in Patients with Moderate to Severe Pain Associated with Chronic Osteoarthritis.

Objective:  Opioids are recommended for patients with moderate to severe pain due to osteoarthritis (OA), who do not receive adequate analgesia from nonopioid treatment. The objective of this study...

Clinical efficacy of OROS(®) hydromorphone in patients suffering from severe chronic pain: A Study undertaken in routine clinical practice.

INTRODUCTION: Strong opioids are efficient drugs for treating chronic pain. In cancer patients, strong opioids are the mainstay of pain management, but in non-cancer pain caution is advised due to pos...

The use of High Doses of Oxycodone in an Acute Palliative Care Unit.

A retrospective study of patients who were prescribed controlled-release oxycodone (CRO) in a period of 3 years (2006-2008) was performed. A total of 212 patients were prescribed at discharge CRO for...

Outcome of opioid switching 4 weeks after discharge from a palliative care unit.

Abstract Despite the favorable effects reported with opioid switching performed in a specialized unit in the short term, data on long-term basis are poor, particularly after discharging patients hom...

Clinical Trials [ 6749 Associated Clinical Trials listed on BioPortfolio]

Study of the Effectiveness and Tolerability of OROS Hydromorphone HCI SR(Slow-release) Tablets and Immediate-Release Hydromorphone Tablets in Patients With Chronic Pain

The purpose of this study was to characterize a safe and effective means of conversion and titration to an appropriate dose of hydromorphone HCI, to demonstrate comparable efficacy of OROS...

A Repeated-Dose Evaluation of a Pain Relieving Drug Use and Safety of OROS Hydromorphone HCI in Patients With Chronic Non-Malignant Pain

The purpose of this repeated dose study is to develop recommended dosing information for initiation of therapy with OROS Hydromorphone in patients with chronic non-malignant pain convertin...

A Repeated-Dose Evaluation of Use of a Pain Relieving Drug and Safety of OROS Hydromorphone HCI in Patients With Chronic Cancer Pain

The purpose of this repeated dose study is to develop recommended dosing information for initiation of therapy with OROS Hydromorphone HCI (slow release) in patients with chronic cancer pa...

A Double-Blind Study of Controlled Release OROS Hydromorphone Compared to Placebo in Patients With Chronic OA Pain

To evaluate the efficacy of OROS Hydromorphone in reducing moderate to severe chronic pain in patients with Osteoarthritis (OA) Pain

Study to Test the Effectiveness of Controlled-Release OROS® Hydromorphone HCl Compared to Placebo in Patients With Chronic Low Back Pain

This study will test an experimental drug called OROS® hydromorphone hydrochloride (HCl), a once daily opioid analgesic that can relieve pain. A large number of clinical studies have been...

Search BioPortfolio:
Advertisement
Advertisement