Gallstone Disease: Basic Mechanisms, Diagnosis and Therapy.
Summary of "Gallstone Disease: Basic Mechanisms, Diagnosis and Therapy."
Gallstone disease is one of the most common gastroenterological diseases and represents a major burden for our heath care systems. Cholesterol gallstones, responsible for about 90% of stones, represent a multifactorial disease with an important genetic component. Most gallstone-carriers remain asymptomatic and hence in general, they not need any therapy. In contrast those with symptomatic (biliary colic) or complicated gallstone disease (cholecystitis, obstructive cholangitis, biliary pancreatitis) have to be treated interdisciplinarily by surgeons and endoscopists. Laparoscopic cholecystectomy represents the causal therapy to avoid recurrent symptoms as well as the therapy of choice for cholecystitis as the most common complication of gallstone disease. Bile duct stones and the associated complications (cholangitis, biliary pancreatitis) are primarily treated endoscopically.
Affiliation
Klinik für Innere Medizin II, Universitätsklinikum des Saarlandes, Homburg.
Journal Details
This article was published in the following journal.
Name: Praxis
ISSN: 1661-8157
Pages: 1403-1412
Links
- PubMed Source: http://www.ncbi.nlm.nih.gov/pubmed/22086379
- DOI: http://dx.doi.org/10.1024/1661-8157/a000721
Medical and Biotech [MESH] Definitions
Gestalt Therapy
A form of psychotherapy with emphasis on the interplay of organism and environment. Basic to this therapy is the development of awareness and maturity, as well as self-confidence.
Clinical Laboratory Techniques
Techniques used to carry out clinical investigative procedures in the diagnosis and therapy of disease.
Clinical Chemistry Tests
Laboratory tests demonstrating the presence of physiologically significant substances in the blood, urine, tissue, and body fluids with application to the diagnosis or therapy of disease.
Fluid Therapy
Therapy whose basic objective is to restore the volume and composition of the body fluids to normal with respect to WATER-ELECTROLYTE BALANCE. Fluids may be administered intravenously, orally, by intermittent gavage, or by HYPODERMOCLYSIS.
Diagnosis, Oral
Examination of the mouth and teeth toward the identification and diagnosis of intraoral disease or manifestation of non-oral conditions.
PubMed Articles
Gallstone pancreatitis in older patients: Are we operating enough?
The recommended therapy for mild gallstone pancreatitis is cholecystectomy on initial hospitalization.
Chronic percutaneous gallstone discharge following videothoracoscopic decortication.
Computed tomographic imaging is not recommended as an essential prerequisite in surgery for pleuro-pulmonary sepsis in the current guidelines. We highlight one consequent pitfall and its sequelae. We...
Multiple mucin genes polymorphisms are associated with gallstone disease in Chinese men.
Gallstone is a complex disease caused by multiple environmental and genetic factors. One of these is mucin glycoproteins. This case-control study aimed to investigate the association between single nu...
Recurrence of gallstones after cholecystectomy is associated with ABCG5/8 genotype.
BACKGROUND: Gallstone disease is a frequent and economically highly relevant disorder, with cholecystectomy representing one of the most frequently performed operations world-wide. Gallstone recurrenc...
Mucin genes in gallstone disease.
Gallstone disease is a complex disorder that can be caused by environmental influences, common genetic factors and their interactions. Three major pathogenic abnormalities are considered to involve in...
Clinical Trials
Early Versus Delayed Surgery for Gallstone Pancreatitis
While there exists consensus among surgeons that patients with gallstone pancreatitis should undergo cholecystectomy to prevent recurrence, the precise timing of laparoscopic cholecystecto...
Basic Sensations Coming From the Bladder
A major complication in studies to identify the nature of bladder sensations is language. It is difficult, if not near impossible, for the lay person, with no knowledge of physiology, anat...
Pulmonary Hypertension--Mechanisms and Family Registry
To establish a registry of primary pulmonary hypertension (PPH), a lethal disease which causes progressive obstruction of small pulmonary arteries and to investigate basic mechanisms of th...
Basic Mechanisms of Meditation and Cardiovascular Disease in Older Blacks
The purpose of this study is to evaluate the effects of meditation on older African Americans with documented cardiovascular disease (CVD).
The purpose of this study is to determine the effects of Logan Basic Technique on symptoms of dysmenorrhea.
