Mitochondrial involvement in carbachol-induced intracellular Ca(2+) mobilization and contraction in rat gastric smooth muscle.
Summary of "Mitochondrial involvement in carbachol-induced intracellular Ca(2+) mobilization and contraction in rat gastric smooth muscle."
Mitochondria are important modulators of Ca(2+) homeostasis. However, it is not clear if they modulate and participate in smooth muscle signaling and contraction. The aim of the present work was to investigate the role of mitochondria in Ca(2+) transients and contraction induced by metabotropic muscarinic receptor activation in rat gastric smooth muscle.
Department of Pharmacology, Paulista School of Medicine, Federal University of São Paulo (UNIFESP/EPM), Brazil.
This article was published in the following journal.
Name: Life sciences
- PubMed Source: http://www.ncbi.nlm.nih.gov/pubmed/21871904
- DOI: http://dx.doi.org/10.1016/j.lfs.2011.08.003
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