Mitochondrial involvement in carbachol-induced intracellular Ca(2+) mobilization and contraction in rat gastric smooth muscle.

00:37 EDT 3rd August 2015 | BioPortfolio

Summary of "Mitochondrial involvement in carbachol-induced intracellular Ca(2+) mobilization and contraction in rat gastric smooth muscle."

Mitochondria are important modulators of Ca(2+) homeostasis. However, it is not clear if they modulate and participate in smooth muscle signaling and contraction. The aim of the present work was to investigate the role of mitochondria in Ca(2+) transients and contraction induced by metabotropic muscarinic receptor activation in rat gastric smooth muscle.

Affiliation

Department of Pharmacology, Paulista School of Medicine, Federal University of São Paulo (UNIFESP/EPM), Brazil.

Journal Details

This article was published in the following journal.

Name: Life sciences
ISSN: 1879-0631
Pages: 757-64

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